Gut Hormones Change With Body Weight: Normal, Overweight, and Obese Have Different Profiles
Gastric sensorimotor function and gut hormone profiles (ghrelin, CCK, PYY) differed progressively between normal weight, overweight, and obese individuals, revealing body weight-dependent gut-brain signaling changes.
Quick Facts
What This Study Found
Gastric accommodation, sensitivity, emptying, and gut hormones (ghrelin, CCK, PYY) showed progressive changes from normal through overweight to obese, with disrupted fasting/postprandial hormone profiles providing the hormonal basis for weight-dependent appetite dysfunction.
Key Numbers
How They Did This
cross-sectional study on neuropeptides, weight-loss.
Why This Research Matters
Relevant for neuropeptides, weight-loss, gut-healing.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Gastric accommodation, sensitivity, emptying, and gut hormones (ghrelin, CCK, PYY) showed progressive changes from normal through overweight to obese,
- Evidence Grade:
- strong evidence.
- Study Age:
- Published in 2006.
- Original Title:
- Gastric sensorimotor functions and hormone profile in normal weight, overweight, and obese people.
- Published In:
- Gastroenterology, 131(6), 1717-24 (2006)
- Authors:
- Vazquez Roque, Maria I, Camilleri, Michael(6), Stephens, Debra A, Jensen, Michael D, Burton, Duane D, Baxter, Kari L, Zinsmeister, Alan R
- Database ID:
- RPEP-01193
Evidence Hierarchy
A snapshot of a population at one point in time.
What do these levels mean? →Frequently Asked Questions
What was studied?
Gut Hormones Change With Body Weight: Normal, Overweight, and Obese Have Different Profiles
What was found?
Gastric sensorimotor function and gut hormone profiles (ghrelin, CCK, PYY) differed progressively between normal weight, overweight, and obese individuals, revealing body weight-dependent gut-brain signaling changes.
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Cite This Study
https://rethinkpeptides.com/research/RPEP-01193APA
Vazquez Roque, Maria I; Camilleri, Michael; Stephens, Debra A; Jensen, Michael D; Burton, Duane D; Baxter, Kari L; Zinsmeister, Alan R. (2006). Gastric sensorimotor functions and hormone profile in normal weight, overweight, and obese people.. Gastroenterology, 131(6), 1717-24.
MLA
Vazquez Roque, Maria I, et al. "Gastric sensorimotor functions and hormone profile in normal weight, overweight, and obese people.." Gastroenterology, 2006.
RethinkPeptides
RethinkPeptides Research Database. "Gastric sensorimotor functions and hormone profile in normal..." RPEP-01193. Retrieved from https://rethinkpeptides.com/research/vazquez-2006-gastric-sensorimotor-functions-and
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.