Cannabis Research Database
7352 Peer-Reviewed Studies
Every study in our database is verified, summarized in plain English, and linked to our articles.
Showing 7352 of 7352 studies
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Managing Heart Failure and Kidney Disease Together: KDIGO Expert Consensus on Emerging Therapies Including GLP-1 Agonists
KDIGO expert consensus highlights GLP-1 receptor agonists and other emerging therapies as beneficial for patients with coexisting heart failure and chronic kidney disease.
Lam, Carolyn S P; Bozkurt, Biykem; Cherney, David Z I; Ezekowitz, Justin A; Jardine, Meg J; Khan, Sadiya S; Madero, Magdalena; Sarnak, Mark J; Ter Maaten, Jozine M; Cheung, Michael; King, Jennifer M; Grams, Morgan E; Jadoul, Michel; Bansal, Nisha · Kidney international
Body Contouring Surgery After GLP-1 Weight Loss Has Similar Complication Rates to Other Methods
A study of 1,002 patients found that body contouring surgery complication rates were similar regardless of whether weight was lost through GLP-1 drugs, bariatric surgery, or lifestyle changes.
Abbott, Erin N; Giannas, Emmanuel; Dorjsuren, Nomongo; King, Daniella; Li, Ruoying; Christopher, Adrienne; Gergoudis, Franklin; Gabriel, Allen; Perdikis, Galen; Assi, Patrick · Aesthetic surgery journal
Does Semaglutide Increase Risk of a Rare Eye Condition? Meta-Analysis of Nearly 5 Million Patients
Meta-analysis of nearly 5 million patients finds no consistent overall link between semaglutide and NAION, a rare eye condition, though a possible signal in diabetes patients needs further study.
Abdelaal, Abdelaziz; Serhan, Hashem Abu; Alsaadi, Mustafa; Yaldo, Luke; Gaier, Eric D; Elhusseiny, Abdelrahman M · Ophthalmology
Liraglutide Protected Against Alzheimer's-Like Brain Damage in Rats Through a Newly Identified Pathway
Liraglutide improved memory and reduced Alzheimer's markers in rats through a newly discovered pathway connecting oxidized LDL to amyloid-producing enzyme BACE1.
Abo El-Magd, Nada F; Ramadan, Nehal M; Eraky, Salma M · Communications biology
GLP-1 Drug Dulaglutide Triggered Rare Diabetic Emergency Despite Normal Blood Sugar
Case report describes euglycemic diabetic ketoacidosis in a gastroparesis patient after starting GLP-1 drug dulaglutide, expanding EDKA risk awareness beyond SGLT-2 inhibitors.
Adrejiya, Parth; Alhujaily, Ensaf; Abubaker, Mohammad; Dorenbush, Chelsae; Khouzam, Rami · Proceedings (Baylor University. Medical Center)
Wheelchair-Bound Patient With Rare Metastatic Neck Tumor Has Exceptional Response to Peptide Radiation Therapy — Twice
A wheelchair-bound patient with metastatic carotid body tumor had an exceptional response to retreatment with 177Lu-DOTATATE peptide radiation therapy after her cancer returned.
Aggarwal, Piyush; Satapathy, Swayamjeet; Sarungbam, Bidya; Sood, Ashwani; Kumar, Rajender; Goyal, Shikha; Mittal, Bhagwant Rai · Clinical nuclear medicine
Peptide Biomarkers for Long COVID Heart Damage: What Blood Tests Can Tell Us
Review identifies natriuretic peptides, endothelin-1, and other biomarkers as key tools for detecting and monitoring cardiovascular damage in long COVID patients.
Aguiar, Carlos Eduardo Oliveira; Costa, Juan Marcos Caram; Oliveira, Marina Maria Gomes Leite; Lopes, Caio Ferraz; Lima, Pedro Henrique Melo; Dietrich, Victoria Cenci; Grenfell, Rafaella Fortini Queiroz; de Melo, Fabrício Freire · World journal of cardiology
Antimicrobial Peptides Do More Than Fight Infection — They Also Regulate Blood Clotting and Vessel Repair
Antimicrobial peptides serve as concentration-dependent switches between tissue repair and harmful blood clot inflammation, with platelets actively manufacturing their own peptide repertoire.
Aguilar-Ruiz, Sergio Roberto; Sánchez-Peña, Francisco Javier; Rodríguez-Magadán, Héctor Maximino; Domínguez-Martínez, Miguel Angel; Bernardino-Hernández, Héctor Ulises; Aquino-Domínguez, Alba Soledad · Biomolecules
Nanoparticle Nasal Spray Delivers Oxytocin Directly to the Brain in Mice
PEGylated nanoparticles delivered oxytocin from nose to brain in mice, targeting the olfactory bulb and frontal cortex with reduced systemic exposure.
Ahmad, Naveed; Han, Shunping; Utami, Rifka; Baker, Rafal; Helal, Dina; Li, Zhuoni; Tricklebank, Mark; Paloyelis, Yannis; Wang, Julie; Petrinovic, Marija M; Bansal, Sukhi; Al-Jamal, Khuloud T · Small (Weinheim an der Bergstrasse
Metal Ions Dramatically Strengthen Peptide-Based Hydrogels for Biomaterial Applications
Adding metal ions to peptide-PEG conjugate hydrogels boosted stability by orders of magnitude, creating a tunable platform for biomaterial engineering.
Ahmadi, Mostafa; Wittek, Kamila; Rieger, Hanna Sophie; Thomas, Marius; Hartmann, Lars; Besenius, Pol; Seiffert, Sebastian · Chemistry of materials : a publication of the American Chemical Society
Could GLP-1 Drugs Like Ozempic Help People Quit Smoking and Avoid Weight Gain at the Same Time?
Narrative review exploring whether GLP-1 drugs could help smokers quit while preventing post-cessation weight gain — promising early signals but limited human evidence.
Ahmed, Ghazi Uddin; Zehra, Eiman; Rasheed, Sana; Akhtar, Syed Owais; Raza, Ahmed Asad; Mujaddadi, Khunsha; Samadi, Abedin · Annals of medicine and surgery (2012)
How Vitamin D Boosts the Body's Natural Antiviral Peptides
Review explains how vitamin D stimulates production of antimicrobial peptides in immune and respiratory cells that can directly combat viral infections.
Akimbekov, Nuraly S; Digel, Ilya; Tastambek, Kuanysh; Rodriguez-Raecke, Rea; Kistaubayeva, Aida S; Sakhanova, Svetlana K; Wu, Xia; Razzaque, Mohammed S · Advances in experimental medicine and biology
How Much More Do GLP-1 Drug Users Spend on Healthcare? A US Cost Analysis
GLP-1 drug users with diabetes spent ~$7,000 more annually on healthcare than non-users, with US usage doubling between 2016 and 2020.
Akpan, Nsima; Zhou, Bo; Rasu, Rafia S; Sambamoorthi, Usha · Journal of managed care & specialty pharmacy
Breaking Up Bile Acid Traps Improves Peptide Drug Transport in Lab Tests but Not in Living Animals
Disrupting intestinal bile acid micelles freed trapped peptide drugs in lab tests but failed to improve oral absorption in animals, revealing the multi-barrier challenge of oral peptide delivery.
Al-Tamimi, Zahraa; Feng, Mei; Elballa, Waleed; Houser, Sydney; Hageman, Michael J · Journal of pharmaceutical sciences
SGLT2 Inhibitors vs. GLP-1 Agonists for Type 2 Diabetes: Which Works Better in the Real World?
Real-world data shows SGLT2 inhibitors excel at heart failure prevention while GLP-1 agonists better reduce cardiovascular events and protect kidneys in type 2 diabetes.
Alam, Aftab; Imran, Mohd; Ur Rehman, Zia; Sahoo, Biswa Mohan; Mahapatra, Manoj Kumar · Wiener medizinische Wochenschrift (1946)
Semaglutide in Obese Women With PCOS: Real-World Weight Loss and Metabolic Improvements
Real-world study of 58 obese women with PCOS found semaglutide produced 11.4% body weight loss with improved blood pressure, blood sugar, cholesterol, and menstrual regularity.
Alawami, Fatimah; Novaes, Olivia; Gibney, James; Phelan, Niamh; Behan, Lucy Ann; Owens, Lisa · Irish journal of medical science
Tirzepatide Restored Testosterone and Sperm Quality in Diabetic Rats Better Than Metformin
Tirzepatide reversed diabetes-induced testicular damage and restored reproductive hormones in rats through antioxidant pathway activation, outperforming metformin.
Albokhadaim, Ibrahim · Toxicology research
Kuwait Expert Panel Recommends GLP-1 Drugs for Combined Heart, Kidney, and Metabolic Disease
Kuwaiti experts recommend integrated cardiovascular-kidney-metabolic care with broader GLP-1 RA use, especially semaglutide, to address the country's severe obesity and diabetes burden.
Aldahi, Waleed A; Alenezi, Abdullah; Alessa, Thamer; Alhamdan, Rashed; Al-Humood, Khaldoon A; Alqallaf, Ahmed; Alotaibi, Torki; Alrajab, Heba; Alshammari, Abdulmuhsen M; Alyousef, Anas M; Alsayed Hashem, Asrar; Rizzo, Manfredi · Diabetes therapy : research
GLP-1 Weight Loss Drugs Work Similarly Across Age, Sex, Race, and Starting Weight
Large meta-analysis confirms GLP-1 weight loss drugs work consistently across age, sex, race, BMI, and HbA1c levels.
Alexander, G Caleb; Xiao, Xuya; Dilek, Sophie; Lewis, Sydney; Deng, Qilin; Kim, Minji; Bolanle, Dami; Saldanha, Ian J; Mehta, Hemalkumar B · JAMA internal medicine
Weight Regain After Stopping GLP-1 Medications: How Much and How Fast?
Large EHR study shows patients regain weight after stopping GLP-1 drugs, with patterns varying by how long they used the medication.
Alexander, G Caleb; Xu, Yizhen; Xiao, Xuya; Lewis, Sydney V; Zeger, Scott; Mehta, Hemalkumar B · Obesity (Silver Spring
Major U.S. Obesity Societies Issue New Evidence-Based Guidance on Weight Loss Medications
Three major U.S. obesity organizations release joint GRADE-based guidance on pharmacological management of obesity in adults.
Alexander, Lydia; Purnell, Jonathan Q; Burridge, Karlijn; Cornier, Marc-André; Golden, Angela; Bade, Deborah; Look, Michelle; Nadglowski, Joe; Ávila-Oliver, Camila; Novillo, Francisco; Rojas-Gómez, Ana María; Hussey, Brad; Salas, Ximena Ramos · Obesity (Silver Spring
GLP-1 Medications May Not Increase Hypothyroidism Risk Compared to DPP-4 Inhibitors
Saudi Arabian real-world study finds no increased hypothyroidism risk with GLP-1 drugs compared to DPP-4 inhibitors.
Alfakhri, Almaha; Almadani, Ohoud; Alroba, Raseel; Alrwisan, Adel; Alshaya, Omar; Albogami, Yasser · Pharmacoepidemiology and drug safety
Anti-Doping Lab Maps How Next-Gen Weight Loss Peptides Break Down in the Body
Researchers mapped the metabolic breakdown of three amylin-based weight loss drugs to develop doping detection methods for sports.
Alhalabi, Hana; Borschel, Lisa; Le Foll, Christelle; Thomas, Andreas; Bally, Lia; Thevis, Mario · Journal of pharmaceutical and biomedical analysis
How Common Is GLP-1 Use for Weight Loss in Saudi Arabia's Eastern Province?
Survey reveals GLP-1 weight loss drug use patterns among overweight/obese adults in Eastern Saudi Arabia.
Alhussain, Khalid; Alshakhs, Zainab; Albaqshi, Layla; Alshaqaqiq, Fawatim; Alrabiah, Mohammed; Tripathi, Rina · Healthcare (Basel
Peer-Led Heart Failure Screening Program for Rural Methamphetamine Users
Trial protocol tests community peer workers using BNP screening to detect meth-related heart failure in rural Oregon, with telecardiology follow-up.
Alias-Ferri, Maria; Kersey, Cooper B; Shalen, Evan F; Cook, Ryan; Gregoire, Devin; Hoffman, Kim; Beam, Michelle; Levander, Ximena A; Pertl, Kellie; Stensby, Alexis; Gonzales, Paul; Smith, Shanna; Evernden, Tabetha; Longenecker, Chris T; Korthuis, P Todd; Chan, Brian · Drug and alcohol dependence reports
This database is maintained by the RethinkTHC research team. All studies listed here have been verified against their original publications. If you notice an error or would like to suggest a study for inclusion, please contact us.
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.