BPC-157 Promotes Achilles Tendon-to-Bone Healing AND Opposes Steroid-Induced Healing Failure

BPC-157 accelerated Achilles tendon-to-bone healing at the detachment site in rats and counteracted corticosteroid-induced healing impairment — addressing both normal and steroid-complicated tendon repair.

Krivic, Andrija et al.·Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2006·Moderate EvidenceAnimal StudyAnimal Study
RPEP-01157Animal StudyModerate Evidence2006RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Animal Study
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

BPC-157 promoted tendon-to-bone healing at the Achilles detachment site in rats, improving both normal healing AND opposing corticosteroid-impaired healing — demonstrating efficacy in the clinically challenging scenario of tendon repair during steroid therapy.

Key Numbers

How They Did This

animal-study study on bpc-157, muscle-recovery.

Why This Research Matters

Relevant for bpc-157, muscle-recovery, bone-joint.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding BPC-157 promoted tendon-to-bone healing at the Achilles detachment site in rats, improving both normal healing AND opposing corticosteroid-impaired he
Evidence Grade:
moderate evidence.
Study Age:
Published in 2006.
Original Title:
Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation.
Published In:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 24(5), 982-9 (2006)
Database ID:
RPEP-01157

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / Observational
Case Report / Animal StudyOne case or non-human subjects
This study

Tests effects in animals (usually mice or rats), not humans.

What do these levels mean? →

Frequently Asked Questions

What was studied?

BPC-157 Promotes Achilles Tendon-to-Bone Healing AND Opposes Steroid-Induced Healing Failure

What was found?

BPC-157 accelerated Achilles tendon-to-bone healing at the detachment site in rats and counteracted corticosteroid-induced healing impairment — addressing both normal and steroid-complicated tendon repair.

Read More on RethinkPeptides

Cite This Study

RPEP-01157·https://rethinkpeptides.com/research/RPEP-01157

APA

Krivic, Andrija; Anic, Tomislav; Seiwerth, Sven; Huljev, Dubravko; Sikiric, Predrag. (2006). Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation.. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 24(5), 982-9.

MLA

Krivic, Andrija, et al. "Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation.." Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2006.

RethinkPeptides

RethinkPeptides Research Database. "Achilles detachment in rat and stable gastric pentadecapepti..." RPEP-01157. Retrieved from https://rethinkpeptides.com/research/krivic-2006-achilles-detachment-in-rat

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.