BPC-157 significantly improved healing of completely transected quadriceps muscle in rats, restoring muscle function and histological organization — extending its repair capabilities to major skeletal muscle injuries.
Key findingBPC-157 accelerated healing of transected quadriceps muscle in rats with improved functional recovery and histological organization compared to contro
What the researchers found
BPC-157 accelerated healing of transected quadriceps muscle in rats with improved functional recovery and histological organization compared to controls, demonstrating efficacy for major skeletal muscle injury repair beyond tendon healing.
Why it matters
Relevant for bpc-157, muscle-recovery.
How the study worked
animal-study study on bpc-157, muscle-recovery.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2006.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 24(5), 1109-17
Citation
Staresinic, Mario; Petrovic, Igor; Novinscak, Tomislav; Jukic, Ivana; Pevec, Damira; Suknaic, Slaven; Kokic, Neven; Batelja, Lovorka; Brcic, Luka; Boban-Blagaic, Alenka; Zoric, Zdenka; Ivanovic, Domagoj; Ajduk, Marko; Sebecic, Bozidar; Patrlj, Leonardo; Sosa, Tomislav; Buljat, Gojko; Anic, Tomislav; Seiwerth, Sven; Sikiric, Predrag. (2006). Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157.. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 24(5), 1109-17.