This comprehensive CCK review covers its dual role as a satiety signal (reducing meal size) and digestive hormone (gallbladder contraction, pancreatic secretion), with CCK-A receptors as validated obesity drug targets.
Key findingCCK operates as both the primary gut satiety signal (reducing meal size through vagal afferent and brain CCK-A receptors) and a digestive coordinator
What the researchers found
CCK operates as both the primary gut satiety signal (reducing meal size through vagal afferent and brain CCK-A receptors) and a digestive coordinator (gallbladder contraction, pancreatic secretion) — the most comprehensively characterized gut hormone.
Why it matters
Relevant for neuropeptides, weight-loss, gut-healing.
How the study worked
review study on neuropeptides, weight-loss.
What this study cannot tell us
See abstract.
How to read the evidence
strong evidence.
When this study was published
Published in 2007.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Cholecystokinin.
Current opinion in endocrinology, diabetes, and obesity, 14(1), 63-7
Citation
Chandra, Rashmi; Liddle, Rodger A. (2007). Cholecystokinin.. Current opinion in endocrinology, diabetes, and obesity, 14(1), 63-7.