Gut Hormones Rise Progressively After Gastric Bypass — Explaining Long-Term Weight Loss Success
GLP-1, PYY, and other gut satiety hormones progressively increased over months after Roux-en-Y gastric bypass, suggesting gut adaptation and providing the hormonal explanation for the surgery's sustained appetite suppression.
Quick Facts
What This Study Found
GLP-1 and PYY3-36 progressively increased over months post-RYGB, with the rise correlating with reduced appetite and sustained weight loss — gut hormonal adaptation (not just restriction) explains bariatric surgery's long-term success.
Key Numbers
How They Did This
cohort study on glp-1, weight-loss.
Why This Research Matters
Relevant for glp-1, weight-loss, gut-healing.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding GLP-1 and PYY3-36 progressively increased over months post-RYGB, with the rise correlating with reduced appetite and sustained weight loss — gut hormo
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2006.
- Original Title:
- Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety.
- Published In:
- The British journal of surgery, 93(2), 210-5 (2006)
- Authors:
- Borg, C M(2), le Roux, C W(2), Ghatei, M A(5), Bloom, S R, Patel, A G, Aylwin, S J B
- Database ID:
- RPEP-01119
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Gut Hormones Rise Progressively After Gastric Bypass — Explaining Long-Term Weight Loss Success
What was found?
GLP-1, PYY, and other gut satiety hormones progressively increased over months after Roux-en-Y gastric bypass, suggesting gut adaptation and providing the hormonal explanation for the surgery's sustained appetite suppression.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01119APA
Borg, C M; le Roux, C W; Ghatei, M A; Bloom, S R; Patel, A G; Aylwin, S J B. (2006). Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety.. The British journal of surgery, 93(2), 210-5.
MLA
Borg, C M, et al. "Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety.." The British journal of surgery, 2006.
RethinkPeptides
RethinkPeptides Research Database. "Progressive rise in gut hormone levels after Roux-en-Y gastr..." RPEP-01119. Retrieved from https://rethinkpeptides.com/research/borg-2006-progressive-rise-in-gut
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.