Wheat Fiber Changes Gut Hormones (PYY, Ghrelin) But Doesn't Immediately Affect Appetite

Wheat fiber intake altered postprandial PYY and ghrelin levels without acutely changing appetite or satiety ratings, suggesting gut hormone changes from fiber need time to translate into appetite effects.

Weickert, Martin O et al.·The British journal of nutrition·2006·Moderate EvidenceRCT
RPEP-01194RCTModerate Evidence2006RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
RCT
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Wheat fiber modified postprandial PYY and ghrelin responses without immediate appetite changes, suggesting fiber-induced gut hormone modulation requires chronic exposure rather than acute meal effects for meaningful appetite impact.

Key Numbers

How They Did This

RCT study on neuropeptides, weight-loss.

Why This Research Matters

Relevant for neuropeptides, weight-loss, bioactive-food-peptides.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding Wheat fiber modified postprandial PYY and ghrelin responses without immediate appetite changes, suggesting fiber-induced gut hormone modulation requir
Evidence Grade:
moderate evidence.
Study Age:
Published in 2006.
Original Title:
Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety.
Published In:
The British journal of nutrition, 96(5), 795-8 (2006)
Database ID:
RPEP-01194

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Wheat Fiber Changes Gut Hormones (PYY, Ghrelin) But Doesn't Immediately Affect Appetite

What was found?

Wheat fiber intake altered postprandial PYY and ghrelin levels without acutely changing appetite or satiety ratings, suggesting gut hormone changes from fiber need time to translate into appetite effects.

Read More on RethinkPeptides

Cite This Study

RPEP-01194·https://rethinkpeptides.com/research/RPEP-01194

APA

Weickert, Martin O; Spranger, Joachim; Holst, Jens J; Otto, Bärbel; Koebnick, Corinna; Möhlig, Matthias; Pfeiffer, Andreas F H. (2006). Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety.. The British journal of nutrition, 96(5), 795-8.

MLA

Weickert, Martin O, et al. "Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety.." The British journal of nutrition, 2006.

RethinkPeptides

RethinkPeptides Research Database. "Wheat-fibre-induced changes of postprandial peptide YY and g..." RPEP-01194. Retrieved from https://rethinkpeptides.com/research/weickert-2006-wheatfibreinduced-changes-of-postprandial

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.