Wheat fiber intake altered postprandial PYY and ghrelin levels without acutely changing appetite or satiety ratings, suggesting gut hormone changes from fiber need time to translate into appetite effects.
Key findingWheat fiber modified postprandial PYY and ghrelin responses without immediate appetite changes, suggesting fiber-induced gut hormone modulation requir
What the researchers found
Wheat fiber modified postprandial PYY and ghrelin responses without immediate appetite changes, suggesting fiber-induced gut hormone modulation requires chronic exposure rather than acute meal effects for meaningful appetite impact.
Why it matters
Relevant for neuropeptides, weight-loss, bioactive-food-peptides.
How the study worked
RCT study on neuropeptides, weight-loss.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2006.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety.
The British journal of nutrition, 96(5), 795-8
Citation
Weickert, Martin O; Spranger, Joachim; Holst, Jens J; Otto, Bärbel; Koebnick, Corinna; Möhlig, Matthias; Pfeiffer, Andreas F H. (2006). Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety.. The British journal of nutrition, 96(5), 795-8.