Digested Proteins Release Peptides That Trigger CCK From Gut Hormone Cells
Protein hydrolysates directly stimulated CCK release from enteroendocrine cells and acted as partial CCK1 receptor agonists, revealing how protein digestion products directly trigger satiety hormone secretion.
Quick Facts
What This Study Found
Protein hydrolysates directly stimulated CCK secretion from STC-1 enteroendocrine cells and showed partial CCK1 receptor agonist activity, demonstrating dual mechanisms: dietary peptides both trigger satiety hormone release AND directly activate satiety receptors.
Key Numbers
How They Did This
in-vitro study.
Why This Research Matters
Relevant for bioactive-food-peptides, neuropeptides, weight-loss.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Protein hydrolysates directly stimulated CCK secretion from STC-1 enteroendocrine cells and showed partial CCK1 receptor agonist activity, demonstrati
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2008.
- Original Title:
- Protein hydrolysates induce CCK release from enteroendocrine cells and act as partial agonists of the CCK1 receptor.
- Published In:
- Journal of agricultural and food chemistry, 56(3), 837-43 (2008)
- Authors:
- Foltz, Martin, Ansems, Patrick, Schwarz, Jessica, Tasker, Maria C, Lourbakos, Afrodite, Gerhardt, Cindy C
- Database ID:
- RPEP-01338
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Digested Proteins Release Peptides That Trigger CCK From Gut Hormone Cells
What was found?
Protein hydrolysates directly stimulated CCK release from enteroendocrine cells and acted as partial CCK1 receptor agonists, revealing how protein digestion products directly trigger satiety hormone secretion.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01338APA
Foltz, Martin; Ansems, Patrick; Schwarz, Jessica; Tasker, Maria C; Lourbakos, Afrodite; Gerhardt, Cindy C. (2008). Protein hydrolysates induce CCK release from enteroendocrine cells and act as partial agonists of the CCK1 receptor.. Journal of agricultural and food chemistry, 56(3), 837-43. https://doi.org/10.1021/jf072611h
MLA
Foltz, Martin, et al. "Protein hydrolysates induce CCK release from enteroendocrine cells and act as partial agonists of the CCK1 receptor.." Journal of agricultural and food chemistry, 2008. https://doi.org/10.1021/jf072611h
RethinkPeptides
RethinkPeptides Research Database. "Protein hydrolysates induce CCK release from enteroendocrine..." RPEP-01338. Retrieved from https://rethinkpeptides.com/research/foltz-2008-protein-hydrolysates-induce-cck
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.