Collagen Peptides Reduce Knee and Hip Pain During Daily Activities in 12-Week Trial

5 g daily SCP supplementation for 12 weeks significantly reduced pain at rest (p=0.018) and during walking (p=0.032) per physician evaluation. Participants reported significantly less pain climbing stairs (p=0.040) and kneeling (p=0.014) compared to placebo.

Randomized, placebo-controlled trial. 182 healthy adults (18+ years) with functional knee and hip pain during daily activities. Randomized to 5 g specific collagen peptides (CP-G) or placebo (P-G) for 12 weeks. Pain assessed at baseline and 12 weeks by physician and participants using 10-point numeric rating scale (NRS).

Joint pain is one of the most common health complaints, particularly as people age. An accessible, well-tolerated supplement that can reduce pain during everyday activities like walking and stair climbing could meaningfully improve quality of life for millions of people.

This extends collagen peptide joint research beyond young athletes to a broader adult population, suggesting benefits aren't limited to high-impact exercise-related pain. The mechanism likely involves collagen peptides stimulating cartilage-producing cells (chondrocytes) and reducing joint inflammation.

12-week duration may be too short to detect long-term effects or cartilage structural changes. Pain assessment relies on subjective rating scales. Specific composition of the collagen peptides was standardized but may not apply to all collagen supplements. No imaging to confirm structural joint changes.