Noopept Restores Spatial Memory and Increases BDNF in the Brain After Damage
The nootropic dipeptide Noopept restored spatial memory and increased BDNF immunoreactivity in the hippocampus after brain damage, providing the neurotrophic mechanism for its cognitive-enhancing and neuroprotective effects.
Quick Facts
What This Study Found
Noopept (proline-containing dipeptide) restored spatial memory in brain-lesioned rats and increased hippocampal BDNF immunoreactivity, establishing BDNF upregulation as the neurotrophic mechanism for Noopept's cognitive-enhancing and neuroprotective activities.
Key Numbers
How They Did This
animal-study study on neuropeptides, neuroprotection.
Why This Research Matters
Relevant for neuropeptides, neuroprotection, cognitive-enhancement.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Noopept (proline-containing dipeptide) restored spatial memory in brain-lesioned rats and increased hippocampal BDNF immunoreactivity, establishing BD
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2007.
- Original Title:
- The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer's disease model.
- Published In:
- Journal of psychopharmacology (Oxford, England), 21(6), 611-9 (2007)
- Authors:
- Ostrovskaya, Rita U, Gruden, Marina A, Bobkova, Natalya A, Sewell, Robert D E, Gudasheva, Tatyana A, Samokhin, Alexander N, Seredinin, Sergey B, Noppe, Wim, Sherstnev, Vladimir V, Morozova-Roche, Ludmilla A
- Database ID:
- RPEP-01277
Evidence Hierarchy
Tests effects in animals (usually mice or rats), not humans.
What do these levels mean? →Frequently Asked Questions
What was studied?
Noopept Restores Spatial Memory and Increases BDNF in the Brain After Damage
What was found?
The nootropic dipeptide Noopept restored spatial memory and increased BDNF immunoreactivity in the hippocampus after brain damage, providing the neurotrophic mechanism for its cognitive-enhancing and neuroprotective effects.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01277APA
Ostrovskaya, Rita U; Gruden, Marina A; Bobkova, Natalya A; Sewell, Robert D E; Gudasheva, Tatyana A; Samokhin, Alexander N; Seredinin, Sergey B; Noppe, Wim; Sherstnev, Vladimir V; Morozova-Roche, Ludmilla A. (2007). The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer's disease model.. Journal of psychopharmacology (Oxford, England), 21(6), 611-9.
MLA
Ostrovskaya, Rita U, et al. "The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer's disease model.." Journal of psychopharmacology (Oxford, 2007.
RethinkPeptides
RethinkPeptides Research Database. "The nootropic and neuroprotective proline-containing dipepti..." RPEP-01277. Retrieved from https://rethinkpeptides.com/research/ostrovskaya-2007-the-nootropic-and-neuroprotective
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.