Gut Peptides in Food Intake and Energy: The 2006 Definitive Review
This comprehensive 2006 review covers all major gut peptides (GLP-1, PYY, CCK, ghrelin, oxyntomodulin, amylin, PP) in food intake regulation, with GLP-1 and PYY agonists identified as the most promising obesity drug targets.
Quick Facts
What This Study Found
Complete 2006 mapping of gut peptide appetite regulation: GLP-1 and PYY3-36 as top obesity targets, with CCK, oxyntomodulin, amylin, and PP providing complementary satiety signals — ghrelin as the sole orexigenic gut peptide.
Key Numbers
How They Did This
review study on glp-1, neuropeptides.
Why This Research Matters
Relevant for glp-1, neuropeptides, weight-loss.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Complete 2006 mapping of gut peptide appetite regulation: GLP-1 and PYY3-36 as top obesity targets, with CCK, oxyntomodulin, amylin, and PP providing
- Evidence Grade:
- strong evidence.
- Study Age:
- Published in 2006.
- Original Title:
- Gut peptides in the regulation of food intake and energy homeostasis.
- Published In:
- Endocrine reviews, 27(7), 719-27 (2006)
- Authors:
- Murphy, Kevin G(2), Dhillo, Waljit S(8), Bloom, Stephen R(14)
- Database ID:
- RPEP-01168
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
What was studied?
Gut Peptides in Food Intake and Energy: The 2006 Definitive Review
What was found?
This comprehensive 2006 review covers all major gut peptides (GLP-1, PYY, CCK, ghrelin, oxyntomodulin, amylin, PP) in food intake regulation, with GLP-1 and PYY agonists identified as the most promising obesity drug targets.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01168APA
Murphy, Kevin G; Dhillo, Waljit S; Bloom, Stephen R. (2006). Gut peptides in the regulation of food intake and energy homeostasis.. Endocrine reviews, 27(7), 719-27.
MLA
Murphy, Kevin G, et al. "Gut peptides in the regulation of food intake and energy homeostasis.." Endocrine reviews, 2006.
RethinkPeptides
RethinkPeptides Research Database. "Gut peptides in the regulation of food intake and energy hom..." RPEP-01168. Retrieved from https://rethinkpeptides.com/research/murphy-2006-gut-peptides-in-the
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.