A polymorphism in the ghrelin receptor (GHS-R) gene was associated with bulimia nervosa in a Japanese population, suggesting genetic variation in the ghrelin system contributes to eating disorder risk.
Key findingGHS-R gene polymorphism (Leu72Met) was significantly associated with bulimia nervosa in Japanese women, providing genetic evidence linking ghrelin rec
What the researchers found
GHS-R gene polymorphism (Leu72Met) was significantly associated with bulimia nervosa in Japanese women, providing genetic evidence linking ghrelin receptor variation to eating disorder susceptibility.
Why it matters
Relevant for ghrp, anxiety-mood.
How the study worked
cross-sectional study on ghrp, anxiety-mood.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2006.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population.
Journal of neural transmission (Vienna, Austria : 1996), 113(9), 1279-85
Citation
Miyasaka, K; Hosoya, H; Sekime, A; Ohta, M; Amono, H; Matsushita, S; Suzuki, K; Higuchi, S; Funakoshi, A. (2006). Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population.. Journal of neural transmission (Vienna, Austria : 1996), 113(9), 1279-85.