Ghrelin Receptor Gene Variant Linked to Bulimia Nervosa in Japanese Women

A polymorphism in the ghrelin receptor (GHS-R) gene was associated with bulimia nervosa in a Japanese population, suggesting genetic variation in the ghrelin system contributes to eating disorder risk.

Miyasaka, K et al.·Journal of neural transmission (Vienna·2006·Moderate EvidenceCross-Sectional
RPEP-01166Cross SectionalModerate Evidence2006RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

GHS-R gene polymorphism (Leu72Met) was significantly associated with bulimia nervosa in Japanese women, providing genetic evidence linking ghrelin receptor variation to eating disorder susceptibility.

Key Numbers

How They Did This

cross-sectional study on ghrp, anxiety-mood.

Why This Research Matters

Relevant for ghrp, anxiety-mood.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding GHS-R gene polymorphism (Leu72Met) was significantly associated with bulimia nervosa in Japanese women, providing genetic evidence linking ghrelin rec
Evidence Grade:
moderate evidence.
Study Age:
Published in 2006.
Original Title:
Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population.
Published In:
Journal of neural transmission (Vienna, Austria : 1996), 113(9), 1279-85 (2006)
Database ID:
RPEP-01166

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

What was studied?

Ghrelin Receptor Gene Variant Linked to Bulimia Nervosa in Japanese Women

What was found?

A polymorphism in the ghrelin receptor (GHS-R) gene was associated with bulimia nervosa in a Japanese population, suggesting genetic variation in the ghrelin system contributes to eating disorder risk.

Read More on RethinkPeptides

Cite This Study

RPEP-01166·https://rethinkpeptides.com/research/RPEP-01166

APA

Miyasaka, K; Hosoya, H; Sekime, A; Ohta, M; Amono, H; Matsushita, S; Suzuki, K; Higuchi, S; Funakoshi, A. (2006). Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population.. Journal of neural transmission (Vienna, Austria : 1996), 113(9), 1279-85.

MLA

Miyasaka, K, et al. "Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population.." Journal of neural transmission (Vienna, 2006.

RethinkPeptides

RethinkPeptides Research Database. "Association of ghrelin receptor gene polymorphism with bulim..." RPEP-01166. Retrieved from https://rethinkpeptides.com/research/miyasaka-2006-association-of-ghrelin-receptor

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.