Urotensin II Inversely Correlates With Sympathetic Activity and BNP in Kidney Failure
Urotensin II showed inverse correlation with sympathetic nerve activity and natriuretic peptides in end-stage renal disease, suggesting a counter-regulatory relationship in the cardiorenal axis.
Quick Facts
What This Study Found
Plasma urotensin II inversely correlated with muscle sympathetic nerve activity and cardiac natriuretic peptides in ESRD patients, suggesting urotensin II serves a counter-regulatory role in the sympathetic-peptide axis in cardiorenal disease.
Key Numbers
How They Did This
cross-sectional study on neuropeptides, kidney.
Why This Research Matters
Relevant for neuropeptides, kidney, cardiovascular, natriuretic-peptides.
The Bigger Picture
Advances peptide research with clinical implications.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Plasma urotensin II inversely correlated with muscle sympathetic nerve activity and cardiac natriuretic peptides in ESRD patients, suggesting urotensi
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2005.
- Original Title:
- Urotensin II in end-stage renal disease: an inverse correlate of sympathetic function and cardiac natriuretic peptides.
- Published In:
- Journal of nephrology, 18(6), 727-32 (2005)
- Authors:
- Mallamaci, Francesca(2), Cutrupi, Sebastiano, Pizzini, Patrizia, Tripepi, Giovanni, Zoccali, Carmine
- Database ID:
- RPEP-01068
Evidence Hierarchy
A snapshot of a population at one point in time.
What do these levels mean? →Frequently Asked Questions
What was studied?
Urotensin II Inversely Correlates With Sympathetic Activity and BNP in Kidney Failure
What was found?
Urotensin II showed inverse correlation with sympathetic nerve activity and natriuretic peptides in end-stage renal disease, suggesting a counter-regulatory relationship in the cardiorenal axis.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01068APA
Mallamaci, Francesca; Cutrupi, Sebastiano; Pizzini, Patrizia; Tripepi, Giovanni; Zoccali, Carmine. (2005). Urotensin II in end-stage renal disease: an inverse correlate of sympathetic function and cardiac natriuretic peptides.. Journal of nephrology, 18(6), 727-32.
MLA
Mallamaci, Francesca, et al. "Urotensin II in end-stage renal disease: an inverse correlate of sympathetic function and cardiac natriuretic peptides.." Journal of nephrology, 2005.
RethinkPeptides
RethinkPeptides Research Database. "Urotensin II in end-stage renal disease: an inverse correlat..." RPEP-01068. Retrieved from https://rethinkpeptides.com/research/mallamaci-2005-urotensin-ii-in-endstage
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.