The GI Tract's Neuroendocrine Satiety System: Complete 2007 Review
The complete neuroendocrine satiety system involves gut peptides (GLP-1, PYY, CCK, oxyntomodulin, ghrelin), enteric neural signaling, and central integration — with gut peptide-based drugs as the most promising obesity pharmacotherapy.
Quick Facts
What This Study Found
GI neuroendocrine satiety regulation integrates gut peptide signals (GLP-1, PYY, CCK, oxyntomodulin, ghrelin), enteric neural pathways, and central melanocortin/NPY circuits for comprehensive food intake control — gut peptide drugs leading the obesity treatment pipeline.
Key Numbers
How They Did This
review study on neuropeptides, glp-1.
Why This Research Matters
Relevant for neuropeptides, glp-1, weight-loss.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding GI neuroendocrine satiety regulation integrates gut peptide signals (GLP-1, PYY, CCK, oxyntomodulin, ghrelin), enteric neural pathways, and central me
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2007.
- Original Title:
- Review article: The gastrointestinal tract: neuroendocrine regulation of satiety and food intake.
- Published In:
- Alimentary pharmacology & therapeutics, 26 Suppl 2, 241-50 (2007)
- Authors:
- Maljaars, J, Peters, H P F(2), Masclee, A M
- Database ID:
- RPEP-01267
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
What was studied?
The GI Tract's Neuroendocrine Satiety System: Complete 2007 Review
What was found?
The complete neuroendocrine satiety system involves gut peptides (GLP-1, PYY, CCK, oxyntomodulin, ghrelin), enteric neural signaling, and central integration — with gut peptide-based drugs as the most promising obesity pharmacotherapy.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01267APA
Maljaars, J; Peters, H P F; Masclee, A M. (2007). Review article: The gastrointestinal tract: neuroendocrine regulation of satiety and food intake.. Alimentary pharmacology & therapeutics, 26 Suppl 2, 241-50. https://doi.org/10.1111/j.1365-2036.2007.03550.x
MLA
Maljaars, J, et al. "Review article: The gastrointestinal tract: neuroendocrine regulation of satiety and food intake.." Alimentary pharmacology & therapeutics, 2007. https://doi.org/10.1111/j.1365-2036.2007.03550.x
RethinkPeptides
RethinkPeptides Research Database. "Review article: The gastrointestinal tract: neuroendocrine r..." RPEP-01267. Retrieved from https://rethinkpeptides.com/research/maljaars-2007-review-article-the-gastrointestinal
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.