Gastric Bypass Produces Better Gut Hormone Changes Than Gastric Banding for Weight Loss
Roux-en-Y gastric bypass produced significantly greater GLP-1 and PYY increases than gastric banding, explaining bypass's superior weight loss through better hormonal appetite suppression — the surgery's secret is hormones, not just restriction.
Quick Facts
What This Study Found
RYGB produced significantly greater postprandial GLP-1 and PYY3-36 increases and greater ghrelin suppression than gastric banding, with hormonal changes correlating with superior weight loss — gut hormone modification, not restriction alone, explains bypass superiority.
Key Numbers
How They Did This
cross-sectional study on glp-1, weight-loss.
Why This Research Matters
Relevant for glp-1, weight-loss.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding RYGB produced significantly greater postprandial GLP-1 and PYY3-36 increases and greater ghrelin suppression than gastric banding, with hormonal chang
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2006.
- Original Title:
- Differential effects of gastric bypass and banding on circulating gut hormone and leptin levels.
- Published In:
- Obesity (Silver Spring, Md.), 14(9), 1553-61 (2006)
- Authors:
- Korner, Judith(2), Inabnet, William, Conwell, Irene M, Taveras, Carmen, Daud, Amna, Olivero-Rivera, Lorraine, Restuccia, Nancy L, Bessler, Marc
- Database ID:
- RPEP-01155
Evidence Hierarchy
A snapshot of a population at one point in time.
What do these levels mean? →Frequently Asked Questions
What was studied?
Gastric Bypass Produces Better Gut Hormone Changes Than Gastric Banding for Weight Loss
What was found?
Roux-en-Y gastric bypass produced significantly greater GLP-1 and PYY increases than gastric banding, explaining bypass's superior weight loss through better hormonal appetite suppression — the surgery's secret is hormones, not just restriction.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01155APA
Korner, Judith; Inabnet, William; Conwell, Irene M; Taveras, Carmen; Daud, Amna; Olivero-Rivera, Lorraine; Restuccia, Nancy L; Bessler, Marc. (2006). Differential effects of gastric bypass and banding on circulating gut hormone and leptin levels.. Obesity (Silver Spring, Md.), 14(9), 1553-61.
MLA
Korner, Judith, et al. "Differential effects of gastric bypass and banding on circulating gut hormone and leptin levels.." Obesity (Silver Spring, 2006.
RethinkPeptides
RethinkPeptides Research Database. "Differential effects of gastric bypass and banding on circul..." RPEP-01155. Retrieved from https://rethinkpeptides.com/research/korner-2006-differential-effects-of-gastric
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.