A carbohydrate-restricted diet altered gut peptides (PYY, ghrelin) and adiposity signals (leptin, adiponectin) in metabolic syndrome patients, with hormonal changes correlating with weight loss and metabolic improvements.
Key findingCarbohydrate restriction in metabolic syndrome patients modified gut peptide profiles (reduced ghrelin, altered PYY) and adipokine levels (decreased l
What the researchers found
Carbohydrate restriction in metabolic syndrome patients modified gut peptide profiles (reduced ghrelin, altered PYY) and adipokine levels (decreased leptin, increased adiponectin), with hormonal changes correlating with weight loss and improved metabolic markers.
Why it matters
Relevant for neuropeptides, weight-loss, glp-1.
How the study worked
clinical-trial study on neuropeptides, weight-loss.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2007.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
A carbohydrate-restricted diet alters gut peptides and adiposity signals in men and women with metabolic syndrome.
The Journal of nutrition, 137(8), 1944-50
Citation
Hayes, Matthew R; Miller, Carla K; Ulbrecht, Jan S; Mauger, Joanna L; Parker-Klees, Lynn; Gutschall, Melissa Davis; Mitchell, Diane C; Smiciklas-Wright, Helen; Covasa, Mihai. (2007). A carbohydrate-restricted diet alters gut peptides and adiposity signals in men and women with metabolic syndrome.. The Journal of nutrition, 137(8), 1944-50.