This comprehensive review maps the complete gut hormone appetite regulation system: ghrelin (hunger), GLP-1, PYY, oxyntomodulin, CCK, amylin, PP, and bombesin/GRP (satiety) — the definitive 2006 reference for appetite pharmacology.
Key findingComprehensive mapping of GI appetite hormones: ghrelin as the sole orexigenic signal; GLP-1, PYY3-36, oxyntomodulin, CCK, amylin, PP, and bombesin/GRP
What the researchers found
Comprehensive mapping of GI appetite hormones: ghrelin as the sole orexigenic signal; GLP-1, PYY3-36, oxyntomodulin, CCK, amylin, PP, and bombesin/GRP as anorexigenic signals — each acting through distinct receptors and pathways for integrated satiety control.
Why it matters
Relevant for glp-1, neuropeptides, weight-loss.
How the study worked
review study on glp-1, neuropeptides.
What this study cannot tell us
See abstract.
How to read the evidence
strong evidence.
When this study was published
Published in 2006.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Gastrointestinal hormones regulating appetite.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 361(1471), 1187-209
Citation
Chaudhri, Owais; Small, Caroline; Bloom, Steve. (2006). Gastrointestinal hormones regulating appetite.. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 361(1471), 1187-209.