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Peptides and Addiction

Explore peptide research and guides on peptides and addiction.

Peptides and Addiction

GLP-1 Agonists and Addictive Behavior

Semaglutide and tirzepatide reduce alcohol, nicotine, and cocaine cravings through brain reward circuits. The research evidence from trials to mechanism.

Peptides and Addiction

Orexin Antagonists and Drug-Seeking Behavior

Orexin receptor antagonists reduce drug-seeking for opioids, cocaine, and alcohol in preclinical models. Review of SORA, DORA evidence and clinical trials.

Peptides and Addiction

Vaccines for Nicotine and Cocaine: Can You Immunize Against Addiction?

Nicotine and cocaine vaccines use hapten-peptide conjugates to generate drug-blocking antibodies. NicVAX failed Phase 3. Fentanyl vaccines are entering trials.