Pericardial natriuretic peptide levels at autopsy helped distinguish cardiac from non-cardiac death causes, establishing post-mortem BNP/ANP as forensic markers for cardiac function at time of death.
Key findingPost-mortem pericardial ANP and BNP levels differentiated cardiac from non-cardiac death causes in medico-legal autopsies, with BNP showing the best d
What the researchers found
Post-mortem pericardial ANP and BNP levels differentiated cardiac from non-cardiac death causes in medico-legal autopsies, with BNP showing the best discrimination — establishing natriuretic peptides as forensic biomarkers for cardiac function assessment at death.
Why it matters
Relevant for natriuretic-peptides, cardiovascular.
How the study worked
cross-sectional study.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2007.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Postmortem pericardial natriuretic peptides as markers of cardiac function in medico-legal autopsies.
International journal of legal medicine, 121(1), 28-35
Citation
Zhu, Bao-Li; Ishikawa, Takaki; Michiue, Tomomi; Li, Dong-Ri; Zhao, Dong; Tanaka, Sayaka; Kamikodai, Yasunobu; Tsuda, Kohei; Okazaki, Shuji; Maeda, Hitoshi. (2007). Postmortem pericardial natriuretic peptides as markers of cardiac function in medico-legal autopsies.. International journal of legal medicine, 121(1), 28-35.