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Study breakdown

Ovarian Hormones Regulate Gut Motility and Sensitivity: The Menstrual Cycle-GI Connection

Animal StudyPreliminary evidence
The takeaway

Estrogen and progesterone modulated rat gastric motility and visceral sensitivity, providing a hormonal mechanism for the menstrual cycle-related GI symptoms (bloating, altered motility, sensitivity) experienced by many women.

Key finding

Ovarian steroids (estrogen, progesterone) regulated gastric motility patterns and visceral sensitivity in rats, providing the hormonal mechanism for m

What the researchers found

Ovarian steroids (estrogen, progesterone) regulated gastric motility patterns and visceral sensitivity in rats, providing the hormonal mechanism for menstrual cycle-related GI symptom variations experienced by many women.

Why it matters

Relevant for neuropeptides, gut-healing.

How the study worked

animal-study study on neuropeptides, gut-healing.

What this study cannot tell us

See abstract.

How to read the evidence

preliminary evidence.

When this study was published

Published in 2006.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.
  • Clinical translation to evaluate.

Common questions

What was studied?
Ovarian Hormones Regulate Gut Motility and Sensitivity: The Menstrual Cycle-GI Connection
What was found?
Estrogen and progesterone modulated rat gastric motility and visceral sensitivity, providing a hormonal mechanism for the menstrual cycle-related GI symptoms (bloating, altered motility, sensitivity) experienced by many women.

Read the original research

Regulative effects of ovarian steroids on rat gastric motility and sensitivity.

Sheng li xue bao : [Acta physiologica Sinica], 58(3), 275-80

Citation

Yang, Xia; Liu, Ran; Dong, Yan. (2006). Regulative effects of ovarian steroids on rat gastric motility and sensitivity.. Sheng li xue bao : [Acta physiologica Sinica], 58(3), 275-80.