VIP Expands Its Immune Role: Controlling Th17 Cells in Addition to Th1 and Tregs
VIP regulation of immune responses expanded beyond Th1/Treg balance to include Th17 cell modulation, with VIP suppressing pathogenic Th17 differentiation — broadening its anti-autoimmune therapeutic potential.
Quick Facts
What This Study Found
VIP's immunomodulatory spectrum expanded to include Th17 cell regulation: suppressing pathogenic IL-17 producing cells in addition to its established Th1 suppression and Treg promotion — comprehensive anti-autoimmune peptide with Th1/Th17/Treg triple regulation.
Key Numbers
How They Did This
review study.
Why This Research Matters
Relevant for neuropeptides, immune-function, inflammation.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding VIP's immunomodulatory spectrum expanded to include Th17 cell regulation: suppressing pathogenic IL-17 producing cells in addition to its established
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2008.
- Original Title:
- Vasoactive intestinal peptide-mediated Th17 differentiation: an expanding spectrum of vasoactive intestinal peptide effects in immunity and autoimmunity.
- Published In:
- Annals of the New York Academy of Sciences, 1144, 83-9 (2008)
- Authors:
- Yadav, Mahesh, Goetzl, Edward J
- Database ID:
- RPEP-01438
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
What was studied?
VIP Expands Its Immune Role: Controlling Th17 Cells in Addition to Th1 and Tregs
What was found?
VIP regulation of immune responses expanded beyond Th1/Treg balance to include Th17 cell modulation, with VIP suppressing pathogenic Th17 differentiation — broadening its anti-autoimmune therapeutic potential.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01438APA
Yadav, Mahesh; Goetzl, Edward J. (2008). Vasoactive intestinal peptide-mediated Th17 differentiation: an expanding spectrum of vasoactive intestinal peptide effects in immunity and autoimmunity.. Annals of the New York Academy of Sciences, 1144, 83-9. https://doi.org/10.1196/annals.1418.020
MLA
Yadav, Mahesh, et al. "Vasoactive intestinal peptide-mediated Th17 differentiation: an expanding spectrum of vasoactive intestinal peptide effects in immunity and autoimmunity.." Annals of the New York Academy of Sciences, 2008. https://doi.org/10.1196/annals.1418.020
RethinkPeptides
RethinkPeptides Research Database. "Vasoactive intestinal peptide-mediated Th17 differentiation:..." RPEP-01438. Retrieved from https://rethinkpeptides.com/research/yadav-2008-vasoactive-intestinal-peptidemediated-th17
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.