Low pulse pressure independently predicted mortality and correlated with elevated natriuretic peptides in advanced heart failure, identifying a combined hemodynamic-biomarker death risk profile.
Key findingLow pulse pressure independently predicted mortality in advanced chronic heart failure and was associated with higher BNP/NT-proBNP, identifying a com
What the researchers found
Low pulse pressure independently predicted mortality in advanced chronic heart failure and was associated with higher BNP/NT-proBNP, identifying a combined hemodynamic-peptide risk profile for the highest-risk patients.
Why it matters
Relevant for natriuretic-peptides, cardiovascular.
How the study worked
cohort study on natriuretic-peptides, cardiovascular.
What this study cannot tell us
See abstract.
How to read the evidence
strong evidence.
When this study was published
Published in 2005.
The bigger picture
Advances peptide/biomarker research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Low pulse pressure is independently related to elevated natriuretic peptides and increased mortality in advanced chronic heart failure.
European heart journal, 26(17), 1759-64
Citation
Voors, Adriaan A; Petrie, Colin J; Petrie, Mark C; Charlesworth, Andrew; Hillege, Hans L; Zijlstra, Felix; McMurray, John J; van Veldhuisen, Dirk J. (2005). Low pulse pressure is independently related to elevated natriuretic peptides and increased mortality in advanced chronic heart failure.. European heart journal, 26(17), 1759-64.