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Study breakdown

GLP-1 Drugs for Diabetes in 2008: Exenatide, Sitagliptin, and Pramlintide From a Cost Perspective

ReviewModerate evidence
The takeaway

Three new peptide-based diabetes drugs (exenatide/GLP-1, sitagliptin/DPP-4, pramlintide/amylin) evaluated from a managed care perspective for cost-effectiveness, positioning, and optimal patient selection.

Key finding

Managed care analysis of exenatide (GLP-1 agonist: weight loss, injectable), sitagliptin (DPP-4 inhibitor: oral, weight neutral), and pramlintide (amy

What the researchers found

Managed care analysis of exenatide (GLP-1 agonist: weight loss, injectable), sitagliptin (DPP-4 inhibitor: oral, weight neutral), and pramlintide (amylin analog: injectable, weight loss) for T2DM positioning — incretin drugs transforming diabetes pharmacotherapy economics.

Why it matters

Relevant for glp-1, exenatide, diabetes.

How the study worked

review study.

What this study cannot tell us

See abstract.

How to read the evidence

moderate evidence.

When this study was published

Published in 2008.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.
  • Clinical translation to evaluate.

Common questions

What was studied?
GLP-1 Drugs for Diabetes in 2008: Exenatide, Sitagliptin, and Pramlintide From a Cost Perspective
What was found?
Three new peptide-based diabetes drugs (exenatide/GLP-1, sitagliptin/DPP-4, pramlintide/amylin) evaluated from a managed care perspective for cost-effectiveness, positioning, and optimal patient selection.

Read the original research

Managed care perspective on three new agents for type 2 diabetes.

Journal of managed care pharmacy : JMCP, 14(4), 363-80

Citation

VanDeKoppel, Shawna; Choe, Hae Mi; Sweet, Burgunda V. (2008). Managed care perspective on three new agents for type 2 diabetes.. Journal of managed care pharmacy : JMCP, 14(4), 363-80. https://doi.org/10.18553/jmcp.2008.14.4.363