GLP-1 Drugs for Diabetes in 2008: Exenatide, Sitagliptin, and Pramlintide From a Cost Perspective

Three new peptide-based diabetes drugs (exenatide/GLP-1, sitagliptin/DPP-4, pramlintide/amylin) evaluated from a managed care perspective for cost-effectiveness, positioning, and optimal patient selection.

VanDeKoppel, Shawna et al.·Journal of managed care pharmacy : JMCP·2008·Moderate EvidenceReview
RPEP-01430ReviewModerate Evidence2008RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Review
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Managed care analysis of exenatide (GLP-1 agonist: weight loss, injectable), sitagliptin (DPP-4 inhibitor: oral, weight neutral), and pramlintide (amylin analog: injectable, weight loss) for T2DM positioning — incretin drugs transforming diabetes pharmacotherapy economics.

Key Numbers

How They Did This

review study.

Why This Research Matters

Relevant for glp-1, exenatide, diabetes.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding Managed care analysis of exenatide (GLP-1 agonist: weight loss, injectable), sitagliptin (DPP-4 inhibitor: oral, weight neutral), and pramlintide (amy
Evidence Grade:
moderate evidence.
Study Age:
Published in 2008.
Original Title:
Managed care perspective on three new agents for type 2 diabetes.
Published In:
Journal of managed care pharmacy : JMCP, 14(4), 363-80 (2008)
Database ID:
RPEP-01430

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Summarizes existing research on a topic.

What do these levels mean? →

Frequently Asked Questions

What was studied?

GLP-1 Drugs for Diabetes in 2008: Exenatide, Sitagliptin, and Pramlintide From a Cost Perspective

What was found?

Three new peptide-based diabetes drugs (exenatide/GLP-1, sitagliptin/DPP-4, pramlintide/amylin) evaluated from a managed care perspective for cost-effectiveness, positioning, and optimal patient selection.

Read More on RethinkPeptides

Cite This Study

RPEP-01430·https://rethinkpeptides.com/research/RPEP-01430

APA

VanDeKoppel, Shawna; Choe, Hae Mi; Sweet, Burgunda V. (2008). Managed care perspective on three new agents for type 2 diabetes.. Journal of managed care pharmacy : JMCP, 14(4), 363-80. https://doi.org/10.18553/jmcp.2008.14.4.363

MLA

VanDeKoppel, Shawna, et al. "Managed care perspective on three new agents for type 2 diabetes.." Journal of managed care pharmacy : JMCP, 2008. https://doi.org/10.18553/jmcp.2008.14.4.363

RethinkPeptides

RethinkPeptides Research Database. "Managed care perspective on three new agents for type 2 diab..." RPEP-01430. Retrieved from https://rethinkpeptides.com/research/vandekoppel-2008-managed-care-perspective-on

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.