A new antimicrobial peptide (lactoferrampin) was identified in the N1-domain of bovine lactoferrin, distinct from lactoferricin, expanding the antimicrobial peptide arsenal from a single milk protein.
Key findingLactoferrampin, a novel antimicrobial peptide from the N1-domain of bovine lactoferrin (distinct from lactoferricin in the N-lobe), showed broad antim
What the researchers found
Lactoferrampin, a novel antimicrobial peptide from the N1-domain of bovine lactoferrin (distinct from lactoferricin in the N-lobe), showed broad antimicrobial activity — expanding the number of bioactive peptides derived from this single milk protein.
Why it matters
Relevant for antimicrobial-peptides, infection, peptide-design.
How the study worked
in-vitro study on antimicrobial-peptides, infection.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2004.
The bigger picture
Advances peptide therapeutics/biomarker research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Lactoferrampin: a novel antimicrobial peptide in the N1-domain of bovine lactoferrin.
Peptides, 25(2), 177-83
Citation
van der Kraan, Marieke I A; Groenink, Jasper; Nazmi, Kamran; Veerman, Enno C I; Bolscher, Jan G M; Nieuw Amerongen, Arie V. (2004). Lactoferrampin: a novel antimicrobial peptide in the N1-domain of bovine lactoferrin.. Peptides, 25(2), 177-83.