RethinkPeptides

Research Status research

Explore studies of research status.

Search this research library

Filter by topic, method, and evidence

Specific topicsStudy typeEvidence

You can select more than one topic or evidence level.

Order

Clear filters

RPEP-04964 · 2020

Safe Method to Create Diabetic Monkey Models Using Single Dose of Standard-Grade STZ

Single 100 mg/kg dose of analytical-grade STZ induced complete diabetes in cynomolgus monkeys with destroyed beta cells and <0.5 ng/mL stimulated C-peptide, without organ toxicity.

Liu, Zhengzhao; Lu, Ying; Hu, Wenbao; Hara, Hidetaka; Dai, Yifan; Cai, Zhiming; Mou, Lisha · Animal

RPEP-05296 · 2021

Dual GLP-1/GIP Agonist Shows Promise Against Alzheimer's Disease in Mice

DA4-JC improved cognition, enhanced hippocampal synaptic function, normalized mitochondria via PINK1-Parkin pathway, and reduced both amyloid and p-tau pathology in APP/PS1/Tau transgenic mice.

Cai, Hong-Yan; Yang, Dan; Qiao, Jing; Yang, Jun-Ting; Wang, Zhao-Jun; Wu, Mei-Na; Qi, Jin-Shun; Hölscher, Christian · Animal