H. pylori Infection Changes Stomach Ghrelin Production — Linking Gut Infection to Appetite
Helicobacter pylori infection altered ghrelin expression in human gastric mucosa, with implications for the appetite changes and weight loss commonly associated with H. pylori infection and its treatment.
Quick Facts
What This Study Found
H. pylori infection significantly altered gastric ghrelin mRNA and protein expression, with changes correlating with infection severity and potentially explaining H. pylori-associated appetite changes and the weight gain often seen after eradication treatment.
Key Numbers
How They Did This
cross-sectional study on ghrp, gut-healing.
Why This Research Matters
Relevant for ghrp, gut-healing, infection, hormone-optimization.
The Bigger Picture
Advances peptide therapeutics/biomarker research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding H. pylori infection significantly altered gastric ghrelin mRNA and protein expression, with changes correlating with infection severity and potentiall
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2004.
- Original Title:
- Effect of Helicobacter pylori infection on ghrelin expression in human gastric mucosa.
- Published In:
- The American journal of gastroenterology, 99(11), 2121-7 (2004)
- Authors:
- Tatsuguchi, Atsushi, Miyake, Kazumasa, Gudis, Katya, Futagami, Seiji, Tsukui, Taku, Wada, Ken, Kishida, Teruyuki, Fukuda, Yuh, Sugisaki, Yuichi, Sakamoto, Choitsu
- Database ID:
- RPEP-00986
Evidence Hierarchy
A snapshot of a population at one point in time.
What do these levels mean? →Frequently Asked Questions
What was studied?
H. pylori Infection Changes Stomach Ghrelin Production — Linking Gut Infection to Appetite
What was found?
Helicobacter pylori infection altered ghrelin expression in human gastric mucosa, with implications for the appetite changes and weight loss commonly associated with H. pylori infection and its treatment.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-00986APA
Tatsuguchi, Atsushi; Miyake, Kazumasa; Gudis, Katya; Futagami, Seiji; Tsukui, Taku; Wada, Ken; Kishida, Teruyuki; Fukuda, Yuh; Sugisaki, Yuichi; Sakamoto, Choitsu. (2004). Effect of Helicobacter pylori infection on ghrelin expression in human gastric mucosa.. The American journal of gastroenterology, 99(11), 2121-7.
MLA
Tatsuguchi, Atsushi, et al. "Effect of Helicobacter pylori infection on ghrelin expression in human gastric mucosa.." The American journal of gastroenterology, 2004.
RethinkPeptides
RethinkPeptides Research Database. "Effect of Helicobacter pylori infection on ghrelin expressio..." RPEP-00986. Retrieved from https://rethinkpeptides.com/research/tatsuguchi-2004-effect-of-helicobacter-pylori
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.