Helicobacter pylori infection altered ghrelin expression in human gastric mucosa, with implications for the appetite changes and weight loss commonly associated with H. pylori infection and its treatment.
Key findingH. pylori infection significantly altered gastric ghrelin mRNA and protein expression, with changes correlating with infection severity and potentiall
What the researchers found
H. pylori infection significantly altered gastric ghrelin mRNA and protein expression, with changes correlating with infection severity and potentially explaining H. pylori-associated appetite changes and the weight gain often seen after eradication treatment.
Why it matters
Relevant for ghrp, gut-healing, infection, hormone-optimization.
How the study worked
cross-sectional study on ghrp, gut-healing.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2004.
The bigger picture
Advances peptide therapeutics/biomarker research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Effect of Helicobacter pylori infection on ghrelin expression in human gastric mucosa.
The American journal of gastroenterology, 99(11), 2121-7
Citation
Tatsuguchi, Atsushi; Miyake, Kazumasa; Gudis, Katya; Futagami, Seiji; Tsukui, Taku; Wada, Ken; Kishida, Teruyuki; Fukuda, Yuh; Sugisaki, Yuichi; Sakamoto, Choitsu. (2004). Effect of Helicobacter pylori infection on ghrelin expression in human gastric mucosa.. The American journal of gastroenterology, 99(11), 2121-7.