This review connects natriuretic peptide physiology (ANP, BNP, CNP production, receptors, clearance) to clinical utility (heart failure diagnosis, prognosis, screening, monitoring) — biology to bedside.
Key findingNatriuretic peptide system physiology (ANP/BNP cardiac production, NPR-A/B/C receptors, clearance mechanisms) directly underlies their clinical utilit
What the researchers found
Natriuretic peptide system physiology (ANP/BNP cardiac production, NPR-A/B/C receptors, clearance mechanisms) directly underlies their clinical utility for heart failure diagnosis, prognosis, population screening, and treatment monitoring.
Why it matters
Relevant for natriuretic-peptides, cardiovascular.
How the study worked
review study on natriuretic-peptides, cardiovascular.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2004.
The bigger picture
Advances peptide therapeutics/biomarker research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Natriuretic peptide system: physiology and clinical utility.
Current opinion in critical care, 10(5), 336-41
Citation
Suttner, Stefan W; Boldt, Joachim. (2004). Natriuretic peptide system: physiology and clinical utility.. Current opinion in critical care, 10(5), 336-41.