Serial natriuretic peptide measurements over 2 years after myocardial infarction tracked cardiac recovery and predicted late adverse events in the OPTIMAAL trial substudy — supporting long-term BNP monitoring post-MI.
Key findingSerial NT-proBNP and BNP measurements over 2 years post-MI in the OPTIMAAL trial substudy tracked cardiac recovery trajectory and predicted late cardi
What the researchers found
Serial NT-proBNP and BNP measurements over 2 years post-MI in the OPTIMAAL trial substudy tracked cardiac recovery trajectory and predicted late cardiac events, supporting prolonged natriuretic peptide monitoring for post-infarction risk stratification.
Why it matters
Relevant for natriuretic-peptides, cardiovascular.
How the study worked
cohort study on natriuretic-peptides, cardiovascular.
What this study cannot tell us
See abstract.
How to read the evidence
strong evidence.
When this study was published
Published in 2005.
The bigger picture
Advances peptide/biomarker research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Plasma natriuretic peptides up to 2 years after acute myocardial infarction and relation to prognosis: an OPTIMAAL substudy.
Journal of cardiac failure, 11(7), 492-7
Citation
Squire, Iain B; Ørn, Stein; Ng, Leong L; Manhenke, Cord; Shipley, Lorraine; Aarsland, Torbjorn; Dickstein, Kenneth. (2005). Plasma natriuretic peptides up to 2 years after acute myocardial infarction and relation to prognosis: an OPTIMAAL substudy.. Journal of cardiac failure, 11(7), 492-7.