A Remotely Delivered GLP-1RA-Supported Specialist Weight Management Program in Adults Living With Obesity: Retrospective Service Evaluation.
Quick Facts
What This Study Found
A remote semaglutide-supported weight program achieved 19.1% weight loss in active subscribers at 12 months, with 78% losing 10%+ and 62% losing 15%+. However, 60% of participants became inactive.
Key Numbers
341 baseline participants (82.7% women, mean BMI 37.9). Active at 12 months: 39.6%. Active subscribers: -20.0 kg (-19.1%). 77.7% lost 10%+, 61.5% lost 15%+. 69.6% reported no side effects by month 12.
How They Did This
Retrospective service evaluation of a commercial remote weight program (Second Nature). Participants started Sept-Dec 2023. Paired t-tests for outcomes. Qualitative experience analysis.
Why This Research Matters
While completers achieved impressive results comparable to clinical trials, the 60% dropout rate shows that engagement is the biggest challenge for remote obesity programs, even with effective medication.
What This Study Doesn't Tell Us
60% dropout rate limits generalizability. Weight data available for only 52.5% at 12 months. No intent-to-treat analysis. Single commercial program. UK-specific.
Trust & Context
- Original Title:
- A Remotely Delivered GLP-1RA-Supported Specialist Weight Management Program in Adults Living With Obesity: Retrospective Service Evaluation.
- Published In:
- JMIR formative research, 9, e72577 (2025)
- Authors:
- Richards, Rebecca, Whitman, Michael, Wren, Gina, Campion, Peta
- Database ID:
- RPEP-13260
Evidence Hierarchy
Watches what happens naturally without intervening.
What do these levels mean? →Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-13260APA
Richards, Rebecca; Whitman, Michael; Wren, Gina; Campion, Peta. (2025). A Remotely Delivered GLP-1RA-Supported Specialist Weight Management Program in Adults Living With Obesity: Retrospective Service Evaluation.. JMIR formative research, 9, e72577. https://doi.org/10.2196/72577
MLA
Richards, Rebecca, et al. "A Remotely Delivered GLP-1RA-Supported Specialist Weight Management Program in Adults Living With Obesity: Retrospective Service Evaluation.." JMIR formative research, 2025. https://doi.org/10.2196/72577
RethinkPeptides
RethinkPeptides Research Database. "A Remotely Delivered GLP-1RA-Supported Specialist Weight Man..." RPEP-13260. Retrieved from https://rethinkpeptides.com/research/richards-2025-a-remotely-delivered-glp1rasupported
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.