BPC-157 Treats Experimental Esophagitis With Sphincter Failure in Rats
BPC-157 healed prolonged experimental esophagitis with sphincter failure in rats, improving both mucosal healing and sphincter function — addressing the complete pathology of reflux disease.
Quick Facts
What This Study Found
BPC-157 healed prolonged esophagitis and improved lower esophageal sphincter function in a rat reflux model with sphincter failure, addressing both mucosal damage AND the mechanical cause (sphincter dysfunction) of reflux disease.
Key Numbers
How They Did This
animal-study study on bpc-157, gut-healing.
Why This Research Matters
Relevant for bpc-157, gut-healing.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding BPC-157 healed prolonged esophagitis and improved lower esophageal sphincter function in a rat reflux model with sphincter failure, addressing both mu
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2006.
- Original Title:
- An experimental model of prolonged esophagitis with sphincter failure in the rat and the therapeutic potential of gastric pentadecapeptide BPC 157.
- Published In:
- Journal of pharmacological sciences, 102(3), 269-77 (2006)
- Authors:
- Petrovic, Igor(3), Dobric, Ivan(6), Drvis, Petar(3), Shejbal, Drazen, Brcic, Luka, Blagaic, Alenka Boban, Batelja, Lovorka, Kokic, Neven, Tonkic, Ante, Mise, Stjepan, Baotic, Tomislav, Staresinic, Mario, Radic, Bozo, Jakir, Ana, Vuksic, Tihomir, Anic, Tomislav, Seiwerth, Sven, Sikiric, Predrag
- Database ID:
- RPEP-01177
Evidence Hierarchy
Tests effects in animals (usually mice or rats), not humans.
What do these levels mean? →Frequently Asked Questions
What was studied?
BPC-157 Treats Experimental Esophagitis With Sphincter Failure in Rats
What was found?
BPC-157 healed prolonged experimental esophagitis with sphincter failure in rats, improving both mucosal healing and sphincter function — addressing the complete pathology of reflux disease.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01177APA
Petrovic, Igor; Dobric, Ivan; Drvis, Petar; Shejbal, Drazen; Brcic, Luka; Blagaic, Alenka Boban; Batelja, Lovorka; Kokic, Neven; Tonkic, Ante; Mise, Stjepan; Baotic, Tomislav; Staresinic, Mario; Radic, Bozo; Jakir, Ana; Vuksic, Tihomir; Anic, Tomislav; Seiwerth, Sven; Sikiric, Predrag. (2006). An experimental model of prolonged esophagitis with sphincter failure in the rat and the therapeutic potential of gastric pentadecapeptide BPC 157.. Journal of pharmacological sciences, 102(3), 269-77.
MLA
Petrovic, Igor, et al. "An experimental model of prolonged esophagitis with sphincter failure in the rat and the therapeutic potential of gastric pentadecapeptide BPC 157.." Journal of pharmacological sciences, 2006.
RethinkPeptides
RethinkPeptides Research Database. "An experimental model of prolonged esophagitis with sphincte..." RPEP-01177. Retrieved from https://rethinkpeptides.com/research/petrovic-2006-an-experimental-model-of
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.