Collagen Peptides From Gelatin Are Absorbed Into Human Blood After Oral Ingestion

Hydroxyproline-containing peptides from oral gelatin/collagen hydrolysate were detected in human blood, proving oral collagen peptides survive digestion and reach the bloodstream — validating collagen supplement bioavailability.

Ohara, Hiroki et al.·Journal of agricultural and food chemistry·2007·Moderate Evidenceclinical-trial
RPEP-01276Clinical TrialModerate Evidence2007RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
clinical-trial
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Hydroxyproline-containing di- and tripeptides from orally ingested gelatin hydrolysate were detected in human plasma, with food-grade collagen hydrolysate producing higher peptide blood levels than gelatin — confirming oral collagen peptide bioavailability.

Key Numbers

How They Did This

clinical-trial study on collagen-peptides, bioavailability.

Why This Research Matters

Relevant for collagen-peptides, bioavailability.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding Hydroxyproline-containing di- and tripeptides from orally ingested gelatin hydrolysate were detected in human plasma, with food-grade collagen hydroly
Evidence Grade:
moderate evidence.
Study Age:
Published in 2007.
Original Title:
Comparison of quantity and structures of hydroxyproline-containing peptides in human blood after oral ingestion of gelatin hydrolysates from different sources.
Published In:
Journal of agricultural and food chemistry, 55(4), 1532-5 (2007)
Database ID:
RPEP-01276

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Collagen Peptides From Gelatin Are Absorbed Into Human Blood After Oral Ingestion

What was found?

Hydroxyproline-containing peptides from oral gelatin/collagen hydrolysate were detected in human blood, proving oral collagen peptides survive digestion and reach the bloodstream — validating collagen supplement bioavailability.

Read More on RethinkPeptides

Cite This Study

RPEP-01276·https://rethinkpeptides.com/research/RPEP-01276

APA

Ohara, Hiroki; Matsumoto, Hitoshi; Ito, Kyoko; Iwai, Koji; Sato, Kenji. (2007). Comparison of quantity and structures of hydroxyproline-containing peptides in human blood after oral ingestion of gelatin hydrolysates from different sources.. Journal of agricultural and food chemistry, 55(4), 1532-5.

MLA

Ohara, Hiroki, et al. "Comparison of quantity and structures of hydroxyproline-containing peptides in human blood after oral ingestion of gelatin hydrolysates from different sources.." Journal of agricultural and food chemistry, 2007.

RethinkPeptides

RethinkPeptides Research Database. "Comparison of quantity and structures of hydroxyproline-cont..." RPEP-01276. Retrieved from https://rethinkpeptides.com/research/ohara-2007-comparison-of-quantity-and

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.