Urinary N-ANP, N-BNP, and CNP detected heart failure non-invasively, with N-BNP showing the best diagnostic performance — a urine test for heart failure that avoids blood draws.
Key findingUrinary N-BNP showed the best diagnostic performance for heart failure detection among urinary natriuretic peptides tested (N-ANP, N-BNP, CNP), offeri
What the researchers found
Urinary N-BNP showed the best diagnostic performance for heart failure detection among urinary natriuretic peptides tested (N-ANP, N-BNP, CNP), offering a non-invasive urine-based alternative to blood sampling.
Why it matters
Relevant for natriuretic-peptides, cardiovascular, clinical-trials.
How the study worked
cross-sectional study on natriuretic-peptides, cardiovascular.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2004.
The bigger picture
Advances peptide/biomarker research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Diagnosis of heart failure using urinary natriuretic peptides.
Clinical science (London, England : 1979), 106(2), 129-33
Citation
Ng, L L; Geeranavar, S; Jennings, S C; Loke, I; O'Brien, R J. (2004). Diagnosis of heart failure using urinary natriuretic peptides.. Clinical science (London, England : 1979), 106(2), 129-33.