Plasma BNP concentrations correlated with myocardial infarct size quantified by thallium-201 SPECT imaging, establishing BNP as a non-invasive marker of infarction extent.
Key findingBNP plasma concentrations correlated significantly with infarct size measured by thallium-201 SPECT in MI patients, providing a blood test surrogate f
What the researchers found
BNP plasma concentrations correlated significantly with infarct size measured by thallium-201 SPECT in MI patients, providing a blood test surrogate for imaging-determined infarction extent.
Why it matters
Relevant for natriuretic-peptides, cardiovascular, clinical-trials.
How the study worked
cross-sectional study on natriuretic-peptides, cardiovascular.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2004.
The bigger picture
Advances peptide/biomarker research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Correlation of plasma concentrations of B-type natriuretic peptide with infarct size quantified by tomographic thallium-201 myocardial scintigraphy in asymptomatic patients with previous myocardial infarction.
Circulation journal : official journal of the Japanese Circulation Society, 68(10), 923-7
Citation
Nakagawa, Kazuya; Umetani, Ken; Fujioka, Daisuke; Sano, Keita; Nakamura, Takamitsu; Kodama, Yasushi; Kitta, Yoshinobu; Ichigi, Yoshihide; Kawabata, Ken-Ichi; Obata, Jyun-Ei; Takano, Hajime; Inobe, Yoshito; Kugiyama, Kiyotaka. (2004). Correlation of plasma concentrations of B-type natriuretic peptide with infarct size quantified by tomographic thallium-201 myocardial scintigraphy in asymptomatic patients with previous myocardial infarction.. Circulation journal : official journal of the Japanese Circulation Society, 68(10), 923-7.