Natriuretic peptide levels predicted 3-year cardiovascular outcomes in Chagas disease patients, establishing BNP/NT-proBNP as prognostic biomarkers for this neglected tropical disease's cardiac complications.
Key findingNatriuretic peptides (BNP, NT-proBNP) predicted 3-year cardiovascular events and mortality in Chagas disease patients, establishing them as prognostic
What the researchers found
Natriuretic peptides (BNP, NT-proBNP) predicted 3-year cardiovascular events and mortality in Chagas disease patients, establishing them as prognostic biomarkers for Chagas cardiomyopathy — a major neglected tropical disease affecting millions.
Why it matters
Relevant for natriuretic-peptides, cardiovascular.
How the study worked
cohort study.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2008.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Prognostic value of natriuretic peptides in Chagas' disease: a 3-year follow-up investigation.
Cardiology, 110(4), 217-25
Citation
Moreira, Maria da Consolação V; Heringer-Walther, Silvia; Wessel, Niels; Moreira Ventura, Tiago; Wang, Yong; Schultheiss, Heinz-Peter; Walther, Thomas. (2008). Prognostic value of natriuretic peptides in Chagas' disease: a 3-year follow-up investigation.. Cardiology, 110(4), 217-25.