Oxytocin and Vasopressin Shape Human Social Brain Function: fMRI Evidence Review

Intranasal oxytocin and vasopressin modulate human social brain function — amygdala, insula, prefrontal cortex — as shown by fMRI, with implications for treating autism, social anxiety, and other social cognition disorders.

Meyer-Lindenberg, Andreas·Progress in brain research·2008·Moderate EvidenceReview
RPEP-01386ReviewModerate Evidence2008RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Review
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Intranasal oxytocin and vasopressin modulate human social brain circuits (amygdala fear, insula empathy, prefrontal evaluation) as demonstrated by fMRI — neuropeptide modulation of social cognition with therapeutic implications for autism and social anxiety.

Key Numbers

How They Did This

review study.

Why This Research Matters

Relevant for oxytocin, neuropeptides, anxiety-mood.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding Intranasal oxytocin and vasopressin modulate human social brain circuits (amygdala fear, insula empathy, prefrontal evaluation) as demonstrated by fMR
Evidence Grade:
moderate evidence.
Study Age:
Published in 2008.
Original Title:
Impact of prosocial neuropeptides on human brain function.
Published In:
Progress in brain research, 170, 463-70 (2008)
Database ID:
RPEP-01386

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Summarizes existing research on a topic.

What do these levels mean? →

Frequently Asked Questions

What was studied?

Oxytocin and Vasopressin Shape Human Social Brain Function: fMRI Evidence Review

What was found?

Intranasal oxytocin and vasopressin modulate human social brain function — amygdala, insula, prefrontal cortex — as shown by fMRI, with implications for treating autism, social anxiety, and other social cognition disorders.

Read More on RethinkPeptides

Cite This Study

RPEP-01386·https://rethinkpeptides.com/research/RPEP-01386

APA

Meyer-Lindenberg, Andreas. (2008). Impact of prosocial neuropeptides on human brain function.. Progress in brain research, 170, 463-70. https://doi.org/10.1016/S0079-6123(08)00436-6

MLA

Meyer-Lindenberg, Andreas. "Impact of prosocial neuropeptides on human brain function.." Progress in brain research, 2008. https://doi.org/10.1016/S0079-6123(08)00436-6

RethinkPeptides

RethinkPeptides Research Database. "Impact of prosocial neuropeptides on human brain function." RPEP-01386. Retrieved from https://rethinkpeptides.com/research/meyer-lindenberg-2008-impact-of-prosocial-neuropeptides

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.