Genetics of Oxytocin and Vasopressin Receptors Shape Human Social Behavior
Genetic variants in oxytocin receptor (OXTR) and vasopressin 1a receptor (AVPR1a) genes are associated with social behavior traits including autism spectrum, pair-bonding, empathy, and social anxiety in humans.
Quick Facts
What This Study Found
AVPR1a and OXTR genetic polymorphisms are associated with human social behavior variation: autism spectrum features, pair-bonding patterns, empathy levels, and social anxiety — establishing the genetic basis for neuropeptide-mediated social behavior.
Key Numbers
How They Did This
review study.
Why This Research Matters
Relevant for oxytocin, neuropeptides, anxiety-mood.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding AVPR1a and OXTR genetic polymorphisms are associated with human social behavior variation: autism spectrum features, pair-bonding patterns, empathy le
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2008.
- Original Title:
- Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between.
- Published In:
- Progress in brain research, 170, 435-49 (2008)
- Authors:
- Israel, Salomon(2), Lerer, Elad(2), Shalev, Idan(2), Uzefovsky, Florina, Reibold, Mathias, Bachner-Melman, Rachel, Granot, Roni, Bornstein, Gary, Knafo, Ariel, Yirmiya, Nurit, Ebstein, Richard P
- Database ID:
- RPEP-01357
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
What was studied?
Genetics of Oxytocin and Vasopressin Receptors Shape Human Social Behavior
What was found?
Genetic variants in oxytocin receptor (OXTR) and vasopressin 1a receptor (AVPR1a) genes are associated with social behavior traits including autism spectrum, pair-bonding, empathy, and social anxiety in humans.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01357APA
Israel, Salomon; Lerer, Elad; Shalev, Idan; Uzefovsky, Florina; Reibold, Mathias; Bachner-Melman, Rachel; Granot, Roni; Bornstein, Gary; Knafo, Ariel; Yirmiya, Nurit; Ebstein, Richard P. (2008). Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between.. Progress in brain research, 170, 435-49. https://doi.org/10.1016/S0079-6123(08)00434-2
MLA
Israel, Salomon, et al. "Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between.." Progress in brain research, 2008. https://doi.org/10.1016/S0079-6123(08)00434-2
RethinkPeptides
RethinkPeptides Research Database. "Molecular genetic studies of the arginine vasopressin 1a rec..." RPEP-01357. Retrieved from https://rethinkpeptides.com/research/israel-2008-molecular-genetic-studies-of
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.