Self-assembling peptides designed from fibrin's coiled-coil structure formed hydrogels with tunable mechanical properties, creating bio-inspired scaffolds that mimic natural wound healing matrix.
Key findingPeptide-polymer hydrogels designed from fibrin's coiled-coil region self-assembled into scaffolds mimicking natural wound healing matrix, with tunable
What the researchers found
Peptide-polymer hydrogels designed from fibrin's coiled-coil region self-assembled into scaffolds mimicking natural wound healing matrix, with tunable mechanical properties suitable for tissue engineering — bio-inspired design from the body's own clotting protein.
Why it matters
Relevant for cyclic-peptides, wound-healing, peptide-design.
How the study worked
in-vitro study.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2008.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Self-assembling peptide-polymer hydrogels designed from the coiled coil region of fibrin.
Biomacromolecules, 9(9), 2438-46
Citation
Jing, Peng; Rudra, Jai S; Herr, Andrew B; Collier, Joel H. (2008). Self-assembling peptide-polymer hydrogels designed from the coiled coil region of fibrin.. Biomacromolecules, 9(9), 2438-46. https://doi.org/10.1021/bm800459v