How Lactoferrin and Lactoferricin Fight Herpes Virus: Blocking Entry at the Cell Surface
Lactoferrin and lactoferricin prevent herpes simplex virus infection by blocking viral attachment to cell surface heparan sulfate — a mechanism applicable to both prevention and treatment of herpes infections.
Quick Facts
What This Study Found
Lactoferrin/lactoferricin anti-HSV activity operates through blocking viral attachment to cell surface heparan sulfate and potentially interfering with early infection events — applicable to both HSV-1 and HSV-2 with topical prevention implications.
Key Numbers
How They Did This
review study on antimicrobial-peptides, infection.
Why This Research Matters
Relevant for antimicrobial-peptides, infection.
The Bigger Picture
Advances peptide research with clinical implications.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Lactoferrin/lactoferricin anti-HSV activity operates through blocking viral attachment to cell surface heparan sulfate and potentially interfering wit
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2005.
- Original Title:
- Anti herpes simplex virus activity of lactoferrin/lactoferricin -- an example of antiviral activity of antimicrobial protein/peptide.
- Published In:
- Cellular and molecular life sciences : CMLS, 62(24), 3002-13 (2005)
- Authors:
- Jenssen, H
- Database ID:
- RPEP-01051
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
What was studied?
How Lactoferrin and Lactoferricin Fight Herpes Virus: Blocking Entry at the Cell Surface
What was found?
Lactoferrin and lactoferricin prevent herpes simplex virus infection by blocking viral attachment to cell surface heparan sulfate — a mechanism applicable to both prevention and treatment of herpes infections.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01051APA
Jenssen, H. (2005). Anti herpes simplex virus activity of lactoferrin/lactoferricin -- an example of antiviral activity of antimicrobial protein/peptide.. Cellular and molecular life sciences : CMLS, 62(24), 3002-13.
MLA
Jenssen, H. "Anti herpes simplex virus activity of lactoferrin/lactoferricin -- an example of antiviral activity of antimicrobial protein/peptide.." Cellular and molecular life sciences : CMLS, 2005.
RethinkPeptides
RethinkPeptides Research Database. "Anti herpes simplex virus activity of lactoferrin/lactoferri..." RPEP-01051. Retrieved from https://rethinkpeptides.com/research/jenssen-2005-anti-herpes-simplex-virus
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.