Curing H. pylori Changes Stomach Ghrelin and Can Cause Weight Gain
H. pylori eradication increased gastric ghrelin expression and was associated with increased appetite and body weight gain, explaining the weight gain commonly reported after successful H. pylori treatment.
Quick Facts
What This Study Found
H. pylori eradication restored gastric ghrelin expression and increased circulating ghrelin levels, correlating with increased appetite and BMI gain — providing the hormonal mechanism for the weight gain commonly observed after successful H. pylori treatment.
Key Numbers
How They Did This
clinical-trial study.
Why This Research Matters
Relevant for neuropeptides, gut-healing.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding H. pylori eradication restored gastric ghrelin expression and increased circulating ghrelin levels, correlating with increased appetite and BMI gain —
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2008.
- Original Title:
- The influence of the eradication of Helicobacter pylori on gastric ghrelin, appetite, and body mass index in patients with peptic ulcer disease.
- Published In:
- Journal of gastroenterology and hepatology, 23 Suppl 2, S278-85 (2008)
- Authors:
- Jang, Eun Jeong, Park, Sang Woon, Park, Ju Sang, Park, Sang Jong, Hahm, Ki-Baik, Paik, So Ya, Sin, Mi Kyung, Lee, Eon Sook, Oh, Sang Woo, Park, Cheol Young, Baik, Hyun Wook
- Database ID:
- RPEP-01359
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Curing H. pylori Changes Stomach Ghrelin and Can Cause Weight Gain
What was found?
H. pylori eradication increased gastric ghrelin expression and was associated with increased appetite and body weight gain, explaining the weight gain commonly reported after successful H. pylori treatment.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01359APA
Jang, Eun Jeong; Park, Sang Woon; Park, Ju Sang; Park, Sang Jong; Hahm, Ki-Baik; Paik, So Ya; Sin, Mi Kyung; Lee, Eon Sook; Oh, Sang Woo; Park, Cheol Young; Baik, Hyun Wook. (2008). The influence of the eradication of Helicobacter pylori on gastric ghrelin, appetite, and body mass index in patients with peptic ulcer disease.. Journal of gastroenterology and hepatology, 23 Suppl 2, S278-85. https://doi.org/10.1111/j.1440-1746.2008.05415.x
MLA
Jang, Eun Jeong, et al. "The influence of the eradication of Helicobacter pylori on gastric ghrelin, appetite, and body mass index in patients with peptic ulcer disease.." Journal of gastroenterology and hepatology, 2008. https://doi.org/10.1111/j.1440-1746.2008.05415.x
RethinkPeptides
RethinkPeptides Research Database. "The influence of the eradication of Helicobacter pylori on g..." RPEP-01359. Retrieved from https://rethinkpeptides.com/research/jang-2008-the-influence-of-the
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.