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Study breakdown

Apelin: A New Heart-Lung Peptide Biomarker Complementing BNP

Cross SectionalModerate evidence
The takeaway

Apelin, a novel peptide, was identified as a plasma marker of cardiopulmonary disease, with levels distinguishing cardiac from respiratory causes of symptoms and complementing natriuretic peptide testing.

Key finding

Plasma apelin levels differentiated between cardiac and pulmonary disease causes and provided complementary prognostic information alongside natriuret

What the researchers found

Plasma apelin levels differentiated between cardiac and pulmonary disease causes and provided complementary prognostic information alongside natriuretic peptides — a new peptide biomarker for cardiopulmonary disease characterization.

Why it matters

Relevant for neuropeptides, natriuretic-peptides, cardiovascular, respiratory.

How the study worked

cross-sectional study on neuropeptides, natriuretic-peptides.

What this study cannot tell us

See abstract.

How to read the evidence

moderate evidence.

When this study was published

Published in 2006.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.
  • Clinical translation to evaluate.

Common questions

What was studied?
Apelin: A New Heart-Lung Peptide Biomarker Complementing BNP
What was found?
Apelin, a novel peptide, was identified as a plasma marker of cardiopulmonary disease, with levels distinguishing cardiac from respiratory causes of symptoms and complementing natriuretic peptide testing.

Read the original research

Apelin: a new plasma marker of cardiopulmonary disease.

Regulatory peptides, 133(1-3), 134-8

Citation

Goetze, Jens Peter; Rehfeld, Jens F; Carlsen, Jørn; Videbaek, Regitze; Andersen, Claus B; Boesgaard, Soeren; Friis-Hansen, Lennart. (2006). Apelin: a new plasma marker of cardiopulmonary disease.. Regulatory peptides, 133(1-3), 134-8.