This review covers lactoferricin's complete spectrum: antibacterial, antifungal, antiviral, antiparasitic, antitumor, and immunomodulatory activities — establishing it as one of the most multifunctional natural peptides known.
Key findingLactoferricin demonstrates comprehensive bioactivities: antibacterial (gram+ and gram-), antifungal, antiviral (HSV, HIV, CMV), antiparasitic, antitum
What the researchers found
Lactoferricin demonstrates comprehensive bioactivities: antibacterial (gram+ and gram-), antifungal, antiviral (HSV, HIV, CMV), antiparasitic, antitumor (direct cytotoxicity), and immunomodulatory — the most versatile natural antimicrobial peptide characterized.
Why it matters
Relevant for antimicrobial-peptides, infection, cancer, immune-function.
How the study worked
review study on antimicrobial-peptides, infection.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2005.
The bigger picture
Advances peptide research with clinical implications.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties.
Cellular and molecular life sciences : CMLS, 62(22), 2588-98
Citation
Gifford, J L; Hunter, H N; Vogel, H J. (2005). Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties.. Cellular and molecular life sciences : CMLS, 62(22), 2588-98.