Gut Hormones in Obese Women With and Without Binge Eating: Different Appetite Hormone Profiles

Obese women with binge eating disorder showed different ghrelin, PYY, and GLP-1 profiles than obese non-bingers, suggesting BED involves specific gut hormone dysregulation beyond obesity-related changes.

Geliebter, Allan et al.·Physiology & behavior·2008·Moderate Evidenceclinical-trial
RPEP-01342Clinical TrialModerate Evidence2008RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
clinical-trial
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Obese women with BED showed distinct postprandial gut peptide profiles (altered ghrelin, PYY3-36, GLP-1) compared to non-binge obese controls, identifying BED-specific gut hormone dysfunction beyond general obesity-related appetite changes.

Key Numbers

How They Did This

clinical-trial study.

Why This Research Matters

Relevant for neuropeptides, glp-1, weight-loss, anxiety-mood.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding Obese women with BED showed distinct postprandial gut peptide profiles (altered ghrelin, PYY3-36, GLP-1) compared to non-binge obese controls, identif
Evidence Grade:
moderate evidence.
Study Age:
Published in 2008.
Original Title:
Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED).
Published In:
Physiology & behavior, 94(5), 696-9 (2008)
Database ID:
RPEP-01342

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Gut Hormones in Obese Women With and Without Binge Eating: Different Appetite Hormone Profiles

What was found?

Obese women with binge eating disorder showed different ghrelin, PYY, and GLP-1 profiles than obese non-bingers, suggesting BED involves specific gut hormone dysregulation beyond obesity-related changes.

Read More on RethinkPeptides

Cite This Study

RPEP-01342·https://rethinkpeptides.com/research/RPEP-01342

APA

Geliebter, Allan; Hashim, Sami A; Gluck, Marci E. (2008). Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED).. Physiology & behavior, 94(5), 696-9. https://doi.org/10.1016/j.physbeh.2008.04.013

MLA

Geliebter, Allan, et al. "Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED).." Physiology & behavior, 2008. https://doi.org/10.1016/j.physbeh.2008.04.013

RethinkPeptides

RethinkPeptides Research Database. "Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in ob..." RPEP-01342. Retrieved from https://rethinkpeptides.com/research/geliebter-2008-appetiterelated-gut-peptides-ghrelin

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.