Obese women with binge eating disorder showed different ghrelin, PYY, and GLP-1 profiles than obese non-bingers, suggesting BED involves specific gut hormone dysregulation beyond obesity-related changes.
Key findingObese women with BED showed distinct postprandial gut peptide profiles (altered ghrelin, PYY3-36, GLP-1) compared to non-binge obese controls, identif
What the researchers found
Obese women with BED showed distinct postprandial gut peptide profiles (altered ghrelin, PYY3-36, GLP-1) compared to non-binge obese controls, identifying BED-specific gut hormone dysfunction beyond general obesity-related appetite changes.
Why it matters
Relevant for neuropeptides, glp-1, weight-loss, anxiety-mood.
How the study worked
clinical-trial study.
What this study cannot tell us
See abstract.
How to read the evidence
moderate evidence.
When this study was published
Published in 2008.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED).
Physiology & behavior, 94(5), 696-9
Citation
Geliebter, Allan; Hashim, Sami A; Gluck, Marci E. (2008). Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED).. Physiology & behavior, 94(5), 696-9. https://doi.org/10.1016/j.physbeh.2008.04.013