Anti-Inflammatory Neuropeptides: The Body's Own Class of Immune-Regulating Drugs
Neuropeptides (VIP, PACAP, alpha-MSH/KPV, CGRP, cortistatin) form an endogenous class of anti-inflammatory immunoregulatory agents, generating Tregs, suppressing Th1/Th17, and resolving inflammation through specific receptors.
Quick Facts
What This Study Found
Anti-inflammatory neuropeptides (VIP, PACAP, alpha-MSH/KPV, CGRP, cortistatin) constitute an endogenous immunoregulatory system: generating regulatory T-cells, suppressing pathogenic Th1/Th17 responses, and promoting inflammation resolution — nature's own anti-inflammatory drug class.
Key Numbers
How They Did This
review study.
Why This Research Matters
Relevant for neuropeptides, inflammation, immune-function.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Anti-inflammatory neuropeptides (VIP, PACAP, alpha-MSH/KPV, CGRP, cortistatin) constitute an endogenous immunoregulatory system: generating regulatory
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2008.
- Original Title:
- Anti-inflammatory neuropeptides: a new class of endogenous immunoregulatory agents.
- Published In:
- Brain, behavior, and immunity, 22(8), 1146-51 (2008)
- Authors:
- Delgado, Mario(10), Ganea, Doina(4)
- Database ID:
- RPEP-01330
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
What was studied?
Anti-Inflammatory Neuropeptides: The Body's Own Class of Immune-Regulating Drugs
What was found?
Neuropeptides (VIP, PACAP, alpha-MSH/KPV, CGRP, cortistatin) form an endogenous class of anti-inflammatory immunoregulatory agents, generating Tregs, suppressing Th1/Th17, and resolving inflammation through specific receptors.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01330APA
Delgado, Mario; Ganea, Doina. (2008). Anti-inflammatory neuropeptides: a new class of endogenous immunoregulatory agents.. Brain, behavior, and immunity, 22(8), 1146-51. https://doi.org/10.1016/j.bbi.2008.06.001
MLA
Delgado, Mario, et al. "Anti-inflammatory neuropeptides: a new class of endogenous immunoregulatory agents.." Brain, 2008. https://doi.org/10.1016/j.bbi.2008.06.001
RethinkPeptides
RethinkPeptides Research Database. "Anti-inflammatory neuropeptides: a new class of endogenous i..." RPEP-01330. Retrieved from https://rethinkpeptides.com/research/delgado-2008-antiinflammatory-neuropeptides-a-new
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.