A synthetic 20-residue porcine lactoferricin peptide showed broad-spectrum antimicrobial activity against E. coli, Staph aureus, and Streptococcus — demonstrating cross-species lactoferricin utility for antimicrobial applications.
Key findingSynthetic 20-amino-acid porcine lactoferricin peptide demonstrated broad-spectrum activity against gram-positive (S. aureus, Streptococcus) and gram-n
What the researchers found
Synthetic 20-amino-acid porcine lactoferricin peptide demonstrated broad-spectrum activity against gram-positive (S. aureus, Streptococcus) and gram-negative (E. coli) bacteria, validating porcine lactoferricin as another species source for antimicrobial peptide development.
Why it matters
Relevant for antimicrobial-peptides, infection.
How the study worked
in-vitro study on antimicrobial-peptides, infection.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2006.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Synthetic porcine lactoferricin with a 20-residue peptide exhibits antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans.
Journal of agricultural and food chemistry, 54(9), 3277-82
Citation
Chen, Hsiao-Ling; Yen, Chih-Ching; Lu, Chien-Yu; Yu, Chia-Hen; Chen, Chuan-Mu. (2006). Synthetic porcine lactoferricin with a 20-residue peptide exhibits antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans.. Journal of agricultural and food chemistry, 54(9), 3277-82.