Lactoferricin Peptides Also Lower Blood Pressure by Blocking ACE — Anti-Infection AND Anti-Hypertension
Lactoferricin-derived peptides showed ACE-inhibitory activity, reducing vasoconstriction — adding blood pressure-lowering potential to lactoferricin's known antimicrobial and anticancer properties.
Quick Facts
What This Study Found
Lactoferricin-related peptides inhibited ACE-dependent vasoconstriction, adding blood pressure-lowering activity to the antimicrobial, anticancer, and immunomodulatory profile of this milk-derived peptide family.
Key Numbers
How They Did This
in-vitro study on antimicrobial-peptides, cardiovascular.
Why This Research Matters
Relevant for antimicrobial-peptides, cardiovascular, bioactive-food-peptides.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Lactoferricin-related peptides inhibited ACE-dependent vasoconstriction, adding blood pressure-lowering activity to the antimicrobial, anticancer, and
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2006.
- Original Title:
- Lactoferricin-related peptides with inhibitory effects on ACE-dependent vasoconstriction.
- Published In:
- Journal of agricultural and food chemistry, 54(15), 5323-9 (2006)
- Authors:
- Centeno, José M, Burguete, María C, Castelló-Ruiz, María(2), Enrique, María, Vallés, Salvador, Salom, Juan B, Torregrosa, Germán, Marcos, José F, Alborch, Enrique, Manzanares, Paloma
- Database ID:
- RPEP-01123
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Lactoferricin Peptides Also Lower Blood Pressure by Blocking ACE — Anti-Infection AND Anti-Hypertension
What was found?
Lactoferricin-derived peptides showed ACE-inhibitory activity, reducing vasoconstriction — adding blood pressure-lowering potential to lactoferricin's known antimicrobial and anticancer properties.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01123APA
Centeno, José M; Burguete, María C; Castelló-Ruiz, María; Enrique, María; Vallés, Salvador; Salom, Juan B; Torregrosa, Germán; Marcos, José F; Alborch, Enrique; Manzanares, Paloma. (2006). Lactoferricin-related peptides with inhibitory effects on ACE-dependent vasoconstriction.. Journal of agricultural and food chemistry, 54(15), 5323-9.
MLA
Centeno, José M, et al. "Lactoferricin-related peptides with inhibitory effects on ACE-dependent vasoconstriction.." Journal of agricultural and food chemistry, 2006.
RethinkPeptides
RethinkPeptides Research Database. "Lactoferricin-related peptides with inhibitory effects on AC..." RPEP-01123. Retrieved from https://rethinkpeptides.com/research/centeno-2006-lactoferricinrelated-peptides-with-inhibitory
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.