Lactoferricin-derived peptides showed ACE-inhibitory activity, reducing vasoconstriction — adding blood pressure-lowering potential to lactoferricin's known antimicrobial and anticancer properties.
Key findingLactoferricin-related peptides inhibited ACE-dependent vasoconstriction, adding blood pressure-lowering activity to the antimicrobial, anticancer, and
What the researchers found
Lactoferricin-related peptides inhibited ACE-dependent vasoconstriction, adding blood pressure-lowering activity to the antimicrobial, anticancer, and immunomodulatory profile of this milk-derived peptide family.
Why it matters
Relevant for antimicrobial-peptides, cardiovascular, bioactive-food-peptides.
How the study worked
in-vitro study on antimicrobial-peptides, cardiovascular.
What this study cannot tell us
See abstract.
How to read the evidence
preliminary evidence.
When this study was published
Published in 2006.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Lactoferricin-related peptides with inhibitory effects on ACE-dependent vasoconstriction.
Journal of agricultural and food chemistry, 54(15), 5323-9
Citation
Centeno, José M; Burguete, María C; Castelló-Ruiz, María; Enrique, María; Vallés, Salvador; Salom, Juan B; Torregrosa, Germán; Marcos, José F; Alborch, Enrique; Manzanares, Paloma. (2006). Lactoferricin-related peptides with inhibitory effects on ACE-dependent vasoconstriction.. Journal of agricultural and food chemistry, 54(15), 5323-9.