Oxytocin Builds Trust in Humans and Prevents Trust Breakdown After Betrayal
Intranasal oxytocin not only increased trust in a trust game but prevented the typical trust reduction after betrayal — shaping both trust formation and the resilience of trust in human social interactions.
Quick Facts
What This Study Found
Intranasal oxytocin in healthy men increased trust behavior AND prevented trust adaptation (trust reduction) after betrayal in a social investment game, shaping the neural circuitry of both trust formation and trust resilience — with implications for social anxiety and autism.
Key Numbers
How They Did This
RCT study.
Why This Research Matters
Relevant for oxytocin, neuroprotection, cognitive-enhancement.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Intranasal oxytocin in healthy men increased trust behavior AND prevented trust adaptation (trust reduction) after betrayal in a social investment gam
- Evidence Grade:
- strong evidence.
- Study Age:
- Published in 2008.
- Original Title:
- Oxytocin shapes the neural circuitry of trust and trust adaptation in humans.
- Published In:
- Neuron, 58(4), 639-50 (2008)
- Authors:
- Baumgartner, Thomas, Heinrichs, Markus(3), Vonlanthen, Aline, Fischbacher, Urs, Fehr, Ernst
- Database ID:
- RPEP-01312
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Oxytocin Builds Trust in Humans and Prevents Trust Breakdown After Betrayal
What was found?
Intranasal oxytocin not only increased trust in a trust game but prevented the typical trust reduction after betrayal — shaping both trust formation and the resilience of trust in human social interactions.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01312APA
Baumgartner, Thomas; Heinrichs, Markus; Vonlanthen, Aline; Fischbacher, Urs; Fehr, Ernst. (2008). Oxytocin shapes the neural circuitry of trust and trust adaptation in humans.. Neuron, 58(4), 639-50. https://doi.org/10.1016/j.neuron.2008.04.009
MLA
Baumgartner, Thomas, et al. "Oxytocin shapes the neural circuitry of trust and trust adaptation in humans.." Neuron, 2008. https://doi.org/10.1016/j.neuron.2008.04.009
RethinkPeptides
RethinkPeptides Research Database. "Oxytocin shapes the neural circuitry of trust and trust adap..." RPEP-01312. Retrieved from https://rethinkpeptides.com/research/baumgartner-2008-oxytocin-shapes-the-neural
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.