Hair Loss Reported With GLP-1 Drugs: A New Safety Signal to Monitor

Case series and review of hair loss associated with GLP-1 receptor agonists identifies a previously underrecognized side effect that may be related to rapid weight loss or direct drug effects.

Alsuwailem, Omar A et al.·Cureus·2025·Preliminary EvidenceReview
RPEP-09909ReviewPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Review
Evidence
Preliminary Evidence
Sample
N=not applicable
Participants
GLP-1 drug users who reported hair loss across FAERS and clinical literature

What This Study Found

Case series and review of hair loss associated with GLP-1 receptor agonists identifies a previously underrecognized side effect that may be related to rapid weight loss or direct drug effects.

Key Numbers

Systematic review of FAERS dermatological adverse events and clinical literature on GLP-1 RA-associated hair loss.

How They Did This

In publication.

Why This Research Matters

Relevant to peptide therapeutics.

The Bigger Picture

Advances peptide therapeutic knowledge.

What This Study Doesn't Tell Us

In publication.

Questions This Raises

  • ?Long-term implications?
  • ?Comparison to evidence?
  • ?Next research?

Trust & Context

Key Stat:
Key finding Case series and review of hair loss associated with GLP-1 receptor agonists identifies a previously
Evidence Grade:
Based on study design.
Study Age:
Published in 2025.
Original Title:
Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use: A Systematic Review.
Published In:
Cureus, 17(9), e92454 (2025)
Database ID:
RPEP-09909

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Summarizes existing research on a topic.

What do these levels mean? →

Frequently Asked Questions

What does this mean?

Case series and review of hair loss associated with GLP-1 receptor agonists identifies a previously underrecognized side effect that may be related to rapid weight loss or direct drug effects.

How reliable?

Consult publication.

Read More on RethinkPeptides

Cite This Study

RPEP-09909·https://rethinkpeptides.com/research/RPEP-09909

APA

Alsuwailem, Omar A; Alanazi, Rawan; Almutairi, Hessa M; Asiree, Rayan H; Almutairi, Wasan; Almutairi, Taghreed M; Zamandar, Alia; Alkhames, Saleh. (2025). Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use: A Systematic Review.. Cureus, 17(9), e92454. https://doi.org/10.7759/cureus.92454

MLA

Alsuwailem, Omar A, et al. "Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use: A Systematic Review.." Cureus, 2025. https://doi.org/10.7759/cureus.92454

RethinkPeptides

RethinkPeptides Research Database. "Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Re..." RPEP-09909. Retrieved from https://rethinkpeptides.com/research/alsuwailem-2025-hair-loss-associated-with

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.