Serial natriuretic peptide measurements over 6 months outperformed single measurements for detecting heart failure progression in elderly patients — trajectory provides more information than snapshots.
Key findingSerial NT-proBNP and BNP measurements over 6 months improved identification of elderly patients with progressive heart failure compared to single base
What the researchers found
Serial NT-proBNP and BNP measurements over 6 months improved identification of elderly patients with progressive heart failure compared to single baseline measurements, with peptide trajectory providing superior diagnostic and prognostic information.
Why it matters
Relevant for natriuretic-peptides, cardiovascular.
How the study worked
cohort study on natriuretic-peptides, cardiovascular.
What this study cannot tell us
See abstract.
How to read the evidence
strong evidence.
When this study was published
Published in 2007.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Natriuretic peptide biomarkers as information indicators in elderly patients with possible heart failure followed over six years: a head-to-head comparison of four cardiac natriuretic peptides.
Journal of cardiac failure, 13(6), 452-61
Citation
Alehagen, Urban; Svensson, Erland; Dahlström, Ulf. (2007). Natriuretic peptide biomarkers as information indicators in elderly patients with possible heart failure followed over six years: a head-to-head comparison of four cardiac natriuretic peptides.. Journal of cardiac failure, 13(6), 452-61.