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Tirzepatide

Explore peptide research and guides on tirzepatide.

Tirzepatide

Tirzepatide's Dual Mechanism vs Single GLP-1 Agonists

Tirzepatide activates both GIP and GLP-1 receptors, producing greater weight loss and glycemic control than GLP-1-only drugs. How the dual mechanism works.

Tirzepatide

Mounjaro vs Zepbound: Same Drug, Different Labels

Mounjaro and Zepbound are both tirzepatide. One is approved for type 2 diabetes, the other for obesity. Here is what differs and what does not.

Tirzepatide

SURMOUNT Trials: Tirzepatide Weight Loss Data

All five SURMOUNT trials explained: 22.5% weight loss in SURMOUNT-1, diabetes prevention at 3 years, and the head-to-head win over semaglutide.

Tirzepatide

Tirzepatide and Body Composition: The Muscle Data

Tirzepatide causes 75% fat loss and 25% lean mass loss in SURMOUNT-1 DXA data. What the evidence shows about muscle preservation on dual GIP/GLP-1 agonists.

Tirzepatide

Tirzepatide Dose Response: Weight Loss at Each Dose

Tirzepatide produces 16%, 21.4%, and 22.5% weight loss at 5 mg, 10 mg, and 15 mg. Here's the dose-response data from every major SURMOUNT trial.

Tirzepatide

What Is Tirzepatide? The Dual GIP/GLP-1 Agonist

Tirzepatide activates both GIP and GLP-1 receptors, producing up to 22.5% weight loss in SURMOUNT-1. Here's how the dual mechanism works and what sets it apart.