Progress in CRF-1 Antagonist Drug Development for Anxiety and Depression

Updated review of CRF-1 receptor antagonist development for anxiety and depression, covering new compounds, clinical trial results, and reasons for mixed success — the continuing quest for stress peptide drugs.

Zorrilla, Eric P et al.·Drug discovery today·2010·
RPEP-017192010RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Updated review of CRF-1 receptor antagonist development for anxiety and depression, covering new compounds, clinical trial results, and reasons for mixed success — the continuing quest for stress peptide drugs.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding Updated review of CRF-1 receptor antagonist development for anxiety and depression, covering new compounds, clinical trial results, and reasons for mi
Evidence Grade:
emerging evidence.
Study Age:
Published in 2010.
Original Title:
Progress in corticotropin-releasing factor-1 antagonist development.
Published In:
Drug discovery today, 15(9-10), 371-83 (2010)
Database ID:
RPEP-01719

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Progress in CRF-1 Antagonist Drug Development for Anxiety and Depression

What was found?

Updated review of CRF-1 receptor antagonist development for anxiety and depression, covering new compounds, clinical trial results, and reasons for mixed success — the continuing quest for stress peptide drugs.

Read More on RethinkPeptides

Related articles coming soon.

Cite This Study

RPEP-01719·https://rethinkpeptides.com/research/RPEP-01719

APA

Zorrilla, Eric P; Koob, George F. (2010). Progress in corticotropin-releasing factor-1 antagonist development.. Drug discovery today, 15(9-10), 371-83. https://doi.org/10.1016/j.drudis.2010.02.011

MLA

Zorrilla, Eric P, et al. "Progress in corticotropin-releasing factor-1 antagonist development.." Drug discovery today, 2010. https://doi.org/10.1016/j.drudis.2010.02.011

RethinkPeptides

RethinkPeptides Research Database. "Progress in corticotropin-releasing factor-1 antagonist deve..." RPEP-01719. Retrieved from https://rethinkpeptides.com/research/zorrilla-2010-progress-in-corticotropinreleasing-factor1

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.